New horizon in autophagy research

W Le, Z Qin - Acta Pharmacologica Sinica, 2013 - nature.com
The word autophagy is derived from the Greek roots “auto”(self) and “phagy”(eating) and
broadly refers to the cellular catabolic processes, in which cytoplasmic materials are …

Potential therapeutic applications of autophagy

DC Rubinsztein, JE Gestwicki, LO Murphy… - Nature reviews Drug …, 2007 - nature.com
Autophagy is a dynamic process of subcellular degradation, which has recently sparked
great interest as it is now recognized to be involved in various developmental processes and …

[图书][B] Autophagy: biology and diseases

W Le - 2020 - Springer
Although only 4 years have passed since the second edition of Autophagy—Biology and
Diseases was published in 2015, basic and clinical studies of autophagy have developed …

[PDF][PDF] Autophagy, a new target for disease treatment

F Xie, LF Li, LX Chen - Science China. Life Sciences, 2013 - core.ac.uk
Since Ashford and Porter first discovered that cells “eat themselves” in 1962, the process
known as autophagy has generated intense interest in both biomedical research and clinical …

[PDF][PDF] Overview of the Minireviews on Autophagy

MS Lee - Molecules and cells, 2018 - koreascience.kr
After coining the term 'autophagy'by Dr. Christian De Duve in 1967 during a study using
glucagon-perfused liver (Deter and de Duve, 1967), researches on autophagy was slow …

Application and interpretation of current autophagy inhibitors and activators

Y Yang, L Hu, H Zheng, C Mao, W Hu… - Acta Pharmacologica …, 2013 - nature.com
Autophagy is the major intracellular degradation system, by which cytoplasmic materials are
delivered to and degraded in the lysosome. As a quality control mechanism for cytoplasmic …

Drug development and treatment of autophagy in other diseases

J Bao, B Liu, C Wu - Autophagy: Biology and Diseases: Clinical Science, 2020 - Springer
In addition to tumors and aging that are associated with autophagy, many other diseases are
also regulated by autophagy, including liver disease, myopathy, immune pathogen infection …

Molecular markers of autophagy

Q Zhu, F Lin - Yao xue xue bao= Acta Pharmaceutica Sinica, 2016 - europepmc.org
Autophagy is a physiological process which delivers the mutant cytoplasmic proteins and
dysfunctional subcellular organs into lysosomes for degradation to generate fuel in the …

[图书][B] Autophagy Processes and Mechanisms

R Dhiman, SK Bhutia - 2023 - books.google.com
Autophagy Processes and Mechanisms details the process of autophagy and its
significance in diseases and aging. It provides insights into autophagy mechanisms and …

Understanding, Targeting, and Hijacking Autophagy

H Xia, X Xu, M Zhou, M Zhang… - Protein Homeostasis in …, 2022 - Wiley Online Library
There are two main pathways of protein degradation in vivo: proteasome and lysosome. As
a conserved intracellular process, autophagy delivers cargoes such as proteins or …