Application of genomewide association studies in complex human disease.

GYY Guo YuanYuan, XL Xiao Li, SL Sun Lin… - 2012 - cabidigitallibrary.org
In the past few years, scientists have been researching many types of complex human
diseases and traits through genomewide association studies (GWAS), such as diabetes …

Current status of genome-wide association study

JW Han, XJ Zhang - Yi Chuan= Hereditas, 2011 - europepmc.org
In past five years, genome-wide association study (GWAS) has proven to be a powerful and
efficient study design in identifying genetic variants associated with complex diseases and …

Genomewide association study: advances, challenges and deliberation

X Tu, LS Shi, F Wang, Q Wang - Sheng li ke xue jin Zhan [Progress …, 2010 - europepmc.org
Genomewide association study (GWAS) is a novel strategy for discovering genetic basis of
human complex disease or trait. It utilizes millions of single nucleotide polymorphisms …

[图书][B] Exploring the genetic architecture of complex diseases with genome-wide association studies

D Chang - 2014 - search.proquest.com
Over the past decade, the number of genome-wide association studies (GWAS) carried out
has increased exponentially. These studies, mostly by investigating single nucleotide …

Genome-wide association studies: progress in identifying genetic biomarkers in common, complex diseases

SF Kingsmore, IE Lindquist, J Mudge… - Biomarker …, 2007 - journals.sagepub.com
Novel, comprehensive approaches for biomarker discovery and validation are urgently
needed. One particular area of methodologic need is for discovery of novel genetic …

Strategies for genome-wide association analysis: gene-centric approach, network-based analysis and copy number variants: 1st Triennium Post Doc Fellowship report

CA Tavares Correia - 2013 - repositorio.insa.pt
Genome-wide association studies (GWAS) have successfully identified numerous genetic
risk factors for many common phenotypes, such as diabetes, Crohn's disease or height …

Genome Wide Association Studies (GWAS) Analysis and Advances in Medical Research

N Naqi - MedERA-Journal of CMH LMC and IOD, 2021 - jcmhlmc.com
Genome-wide association study (GWAS) is an observational study of a genome-wide set of
genetic variants in different individuals to see if any variant is associated with a trait. GWA …

Post-GWAS strategies

SS Kim, J Bhak - Genomics & informatics, 2011 - koreascience.kr
Genome-wide association (GWA) studies are the method of choice for discovering loci
associated with common diseases. More than a thousand GWA studies have reported …

Benefits and limitations of genome-wide association studies

V Tam, N Patel, M Turcotte, Y Bossé, G Paré… - Nature Reviews …, 2019 - nature.com
Genome-wide association studies (GWAS) involve testing genetic variants across the
genomes of many individuals to identify genotype–phenotype associations. GWAS have …

[图书][B] SNP data analysis in genome-wide association studies

C Yang - 2011 - search.proquest.com
Genome-wide association study (GWAS) is a popular strategy in studying complex diseases.
GWAS genotypes 10 5∼ 10 6 single-nucleotide polymorphisms (SNPs) from thousands of …