Folic acid–containing supplements and fortified foods, including enriched cereal–grain
products and ready-to-eat (RTE) cereals, are the primary sources of folic acid intake in the …

This issue of the Journal includes a comprehensive biochemical assessment of folate status
in a representative sample of the American population in the National Health and Nutrition …

The announcement from the Public Health Service (PHS) last week hardly seemed con-
troversial. The PHS urged women of child-bearing age to make sure they consume 400 …

Folate is an essential vitamin for good health. Women of childbearing age are among the
population subgroups that have been shown previously to have low blood folate levels (1 …

Preconception health encompasses health of the nonpregnant individual during their
reproductive years. 1 The goal is to reduce the risk of adverse health effects for the pregnant …

The long and storied history of the B vitamin, folate, began in the 1930s when Wills (1) and
Stokstad and Manning (2) demonstrated that a factor in yeast could prevent megaloblastic …

Purpose: The 1998 mandate to fortify enriched grain products with folic acid in the US aimed
to help prevent neural tube defects (NTDs) by increasing to 50% the proportion of women of …

Background: US adults have access to multiple sources of folic acid. The contribution of
these sources to usual intakes above the tolerable upper intake level (UL)(1000 μg/d) and to …

Monitoring the folate status of the US population through the National Health and Nutrition
Examination Survey (NHANES) has been a public health priority for the last two decades …

Importance: Neural tube defects are among the most common congenital anomalies in the
United States. Periconceptional folic acid supplementation is a primary care-relevant …