天然产物新靶点: 自噬-溶酶体途径

沈汉明 - 中国药理学与毒理学杂志, 2015 - cjpt.magtechjournal.com
Autophagy is an evolutionarily well conserved process in which the cellular components
including damaged subcellular organelles are engulfed in autophagosome and eventually …

天然产物新靶点: 自噬-溶酶体途径(英文)

沈汉明 - 中国药理学与毒理学杂志, 2015 - cqvip.com
Autophagy is an evolutionarily well conserved process in which the cellular components
including damaged subcellular organelles are engulfed in autophagosome and eventually …

[HTML][HTML] New horizon in autophagy research

W Le, Z Qin - Acta Pharmacologica Sinica, 2013 - nature.com
The word autophagy is derived from the Greek roots “auto”(self) and “phagy”(eating) and
broadly refers to the cellular catabolic processes, in which cytoplasmic materials are …

自噬在抗肿瘤药物毒性中的作用与机制研究进展

陈剑, 曾艳, 高子正, 胡誉怀, 颜皓, 徐志飞, 罗沛华… - 药学进展, 2022 - pps.cpu.edu.cn
自噬是真核细胞中高度保守的依赖于溶酶体的胞内降解途径, 在众多生理病理过程中发挥重要
作用. 随着对自噬关键基因与信号通路的深入解析, 自噬与抗肿瘤药物毒性之间的关系也逐渐被 …

Seeking new anti-cancer agents from autophagy-regulating natural products

F Hua, S Shang, ZW Hu - Journal of Asian natural products …, 2017 - Taylor & Francis
Natural products are an important original source of many widely used drugs, including anti-
cancer drugs. Early research efforts for seeking anti-cancer therapy from the natural …

[HTML][HTML] Application and interpretation of current autophagy inhibitors and activators

Y Yang, L Hu, H Zheng, C Mao, W Hu… - Acta Pharmacologica …, 2013 - nature.com
Autophagy is the major intracellular degradation system, by which cytoplasmic materials are
delivered to and degraded in the lysosome. As a quality control mechanism for cytoplasmic …

Advances in studies on active components in Chinese materia medica modulating autophagy

J DAWULIETI - Chinese Traditional and Herbal Drugs, 2014 - pesquisa.bvsalud.org
Autophagy, as a high conserved starvation response mechanism with defensive and
protective effects in eukaryotic cell, is a lysosome-mediated degradation process for non …

调节细胞自噬的中药有效成分研究进展

佳娜提, 姜楠, 寇俊萍, 余伯阳 - 中草药, 2014 - cqvip.com
细胞自噬(autophagy) 是一种进化上高度保守的饥饿应答机制, 是细胞利用溶酶体降解自身受损
的细胞器和大分子物质的过程, 这一特定的过程是细胞存活, 分化, 发育以及维持内环境稳定的 …

[HTML][HTML] Targeting autophagy with natural products as a potential therapeutic approach for cancer

MAA Al-Bari, Y Ito, S Ahmed, N Radwan… - International journal of …, 2021 - mdpi.com
Macro-autophagy (autophagy) is a highly conserved eukaryotic intracellular process of self-
digestion caused by lysosomes on demand, which is upregulated as a survival strategy …

Understanding, Targeting, and Hijacking Autophagy

H Xia, X Xu, M Zhou, M Zhang… - Protein Homeostasis in …, 2022 - Wiley Online Library
There are two main pathways of protein degradation in vivo: proteasome and lysosome. As
a conserved intracellular process, autophagy delivers cargoes such as proteins or …