Potential therapeutic applications of autophagy
DC Rubinsztein, JE Gestwicki, LO Murphy… - Nature reviews Drug …, 2007 - nature.com
Autophagy is a dynamic process of subcellular degradation, which has recently sparked
great interest as it is now recognized to be involved in various developmental processes and …
great interest as it is now recognized to be involved in various developmental processes and …
Seeking new anti-cancer agents from autophagy-regulating natural products.
HF Hua Fang, SS Shang Shuang, HZW Hu ZhuoWei - 2017 - cabidigitallibrary.org
Natural products are an important original source of many widely used drugs, including anti-
cancer drugs. Early research efforts for seeking anti-cancer therapy from the natural …
cancer drugs. Early research efforts for seeking anti-cancer therapy from the natural …
Autophagy in ageing and ageing-related diseases
F Hua, JJ Yu, K Li, ZW Hu - Yao xue xue bao= Acta Pharmaceutica …, 2014 - europepmc.org
Autophagy is an important homeostatic cellular recycling mechanism responsible for
degrading injured or dysfunctional cellular organelles and proteins in all living cells. Aging is …
degrading injured or dysfunctional cellular organelles and proteins in all living cells. Aging is …
Pharmacological inhibitors of autophagy as novel cancer therapeutic agents
Autophagy is an evolutionarily conserved cellular degradative process in which intracellular
components (cellular proteins and organelles) are engulfed in autophagosomes which then …
components (cellular proteins and organelles) are engulfed in autophagosomes which then …
Drug development and treatment of autophagy in other diseases
J Bao, B Liu, C Wu - Autophagy: Biology and Diseases: Clinical Science, 2020 - Springer
In addition to tumors and aging that are associated with autophagy, many other diseases are
also regulated by autophagy, including liver disease, myopathy, immune pathogen infection …
also regulated by autophagy, including liver disease, myopathy, immune pathogen infection …
Autophagy: a new pathway for traditional Chinese medicine
B Cui, JM Yu - Journal of Asian natural products research, 2018 - Taylor & Francis
Autophagy is a major intracellular degradation pathway that sequesters multiple cytoplasmic
components, including accumulated proteins, damaged organelles, or invading micro …
components, including accumulated proteins, damaged organelles, or invading micro …
Recent advances in characterizing natural products that regulate autophagy
Q Zhao, C Peng, C Zheng, XH He… - Anti-Cancer Agents in …, 2019 - ingentaconnect.com
Autophagy, an intricate response to nutrient deprivation, pathogen infection, Endoplasmic
Reticulum (ER)-stress and drugs, is crucial for the homeostatic maintenance in living cells …
Reticulum (ER)-stress and drugs, is crucial for the homeostatic maintenance in living cells …
Phytochemicals as potent modulators of autophagy for cancer therapy
MA Moosavi, A Haghi, M Rahmati, H Taniguchi… - Cancer Letters, 2018 - Elsevier
The dysregulation of autophagy is involved in the pathogenesis of a broad range of
diseases, and accordingly universal research efforts have focused on exploring novel …
diseases, and accordingly universal research efforts have focused on exploring novel …