Autophagic compound database: a resource connecting autophagy‐modulating compounds, their potential targets and relevant diseases
Y Deng, L Zhu, H Cai, G Wang, B Liu - Cell Proliferation, 2018 - Wiley Online Library
Objectives Autophagy, a highly conserved lysosomal degradation process in eukaryotic
cells, can digest long‐lived proteins and damaged organelles through vesicular trafficking …
cells, can digest long‐lived proteins and damaged organelles through vesicular trafficking …
[HTML][HTML] Autophagy modulation as a target for anticancer drug discovery
X Li, H Xu, Y Liu, N An, S Zhao, J Bao - Acta Pharmacologica Sinica, 2013 - nature.com
Autophagy, an evolutionarily conserved catabolic process involving the engulfment and
degradation of non-essential or abnormal cellular organelles and proteins, is crucial for …
degradation of non-essential or abnormal cellular organelles and proteins, is crucial for …
Autophagy: a druggable process
E Morel, M Mehrpour, J Botti, N Dupont… - Annual Review of …, 2017 - annualreviews.org
Macroautophagy (hereafter called autophagy) is a vacuolar, lysosomal pathway for
catabolism of intracellular material that is conserved among eukaryotic cells. Autophagy …
catabolism of intracellular material that is conserved among eukaryotic cells. Autophagy …
Therapeutic targeting of autophagy in disease: biology and pharmacology
Y Cheng, X Ren, WN Hait, JM Yang - Pharmacological reviews, 2013 - ASPET
Autophagy, a process of self-digestion of the cytoplasm and organelles through which
cellular components are recycled for reuse or energy production, is an evolutionarily …
cellular components are recycled for reuse or energy production, is an evolutionarily …
[HTML][HTML] Novel cancer treatments based on autophagy modulation
Autophagy is an intracellular process in response to stimulus by which damaged organelles,
protein aggregates, or invading pathogens, are targeted from autophagic vesicles to …
protein aggregates, or invading pathogens, are targeted from autophagic vesicles to …
[PDF][PDF] Autophagy by natural products in cancer cells
T Efferth, G HJ - Biochem Anal Biochem, 2012 - m.23michael.com
The physiological function of autophagy in normal cells is to maintain cellular homeostasis
in nutrient-deprived states. The degradation of cytoplasmic material serves cell-autonomous …
in nutrient-deprived states. The degradation of cytoplasmic material serves cell-autonomous …
Targeting autophagy in disease: established and new strategies
Macroautophagy/autophagy is an evolutionarily conserved pathway responsible for clearing
cytosolic aggregated proteins, damaged organelles or invading microorganisms …
cytosolic aggregated proteins, damaged organelles or invading microorganisms …
Mechanisms of autophagy and relevant small-molecule compounds for targeted cancer therapy
J Zhang, G Wang, Y Zhou, Y Chen, L Ouyang… - Cellular and Molecular …, 2018 - Springer
Autophagy is an evolutionarily conserved, multi-step lysosomal degradation process for the
clearance of damaged or superfluous proteins and organelles. Accumulating studies have …
clearance of damaged or superfluous proteins and organelles. Accumulating studies have …
[HTML][HTML] New potential pharmacological functions of Chinese herbal medicines via regulation of autophagy
BYK Law, SWF Mok, AG Wu, CWK Lam, MXY Yu… - Molecules, 2016 - mdpi.com
Autophagy is a universal catabolic cellular process for quality control of cytoplasm and
maintenance of cellular homeostasis upon nutrient deprivation and environmental stimulus …
maintenance of cellular homeostasis upon nutrient deprivation and environmental stimulus …
[HTML][HTML] Inhibiting cytoprotective autophagy in cancer therapy: an update on pharmacological small-molecule compounds
L Zhang, Y Zhu, J Zhang, L Zhang… - Frontiers in Pharmacology, 2022 - frontiersin.org
Autophagy is a self-degradation process in which damaged proteins and organelles are
engulfed into autophagosomes for digestion and eventually recycled for cellular metabolism …
engulfed into autophagosomes for digestion and eventually recycled for cellular metabolism …