[引用][C] Small-Molecule Regulators of Autophagy and Their Potential Therapeutic Applications

周宓, 王任小 - 2013

[HTML][HTML] Pharmacologic agents targeting autophagy

H Vakifahmetoglu-Norberg, H Xia… - The Journal of clinical …, 2015 - Am Soc Clin Investig
Autophagy is an important intracellular catabolic mechanism critically involved in regulating
tissue homeostasis. The implication of autophagy in human diseases and the need to …

Advances in the research of the regulation of Chinese traditional medicine monomer and its derivatives on autophagy in non-small cell lung cancer

M Xiang, LI Ruilei, Z Zhang, S Xin - Zhongguo Fei Ai Za Zhi, 2017 - search.proquest.com
非小细胞肺癌 (non-small cell lung cancer, NSCLC) 发病率, 病死率高, 亟待研发高抗癌活性,
低毒副作用的新型疗法. 自噬既可诱发 NSCLC 癌细胞死亡又可介导死亡逃避 …

Research progress of the key targets of autophagy and related drugs in mammalian cells

X WANG, B CHEN, H LI - Chinese Journal of Clinical …, 2018 - manu41.magtech.com.cn
Autophagy is a catabolic process for the degradation and recycling of macromolecules and
organelles, which is activated during stress conditions. It plays an important role in maintain …

Design of small molecule autophagy modulators: a promising druggable strategy

S He, Q Li, X Jiang, X Lu, F Feng, W Qu… - Journal of medicinal …, 2017 - ACS Publications
Autophagy is a lysosome-dependent mechanism of intracellular degradation for maintaining
cellular homeostasis. Dysregulation of autophagy has been verified to be closely linked to a …

Discovery and target identification of small molecule autophagy inhibitors

L Robke - 2017 - 129.217.131.68
Pharmacologically active substances have been applied in medicine for at least 5300 years.
Ever since, mankind has tried to enlarge the assortment of bio-active substances, in order to …

[HTML][HTML] Emerging role of selective autophagy in human diseases

K Mizumura, AMK Choi, SW Ryter - Frontiers in pharmacology, 2014 - frontiersin.org
Autophagy was originally described as a highly conserved system for the degradation of
cytosol through a lysosome-dependent pathway. In response to starvation, autophagy …

[HTML][HTML] Coordination of autophagy with other cellular activities

Y Wang, Z Qin - Acta Pharmacologica Sinica, 2013 - nature.com
The cell biological phenomenon of autophagy has attracted increasing attention in recent
years, partly as a consequence of the discovery of key components of its cellular machinery …

Molecular markers of autophagy

Q Zhu, F Lin - Yao xue xue bao= Acta Pharmaceutica Sinica, 2016 - europepmc.org
Autophagy is a physiological process which delivers the mutant cytoplasmic proteins and
dysfunctional subcellular organs into lysosomes for degradation to generate fuel in the …

Autophagy function and its relationship to pathology, clinical applications, drug metabolism and toxicity

DM Petibone, W Majeed… - Journal of Applied …, 2017 - Wiley Online Library
Autophagy is a cellular process that facilitates nutrient turnover and removal of expended
macromolecules and organelles to maintain homeostasis. The recycling of cytosolic …