Chemical autophagy regulators
YP Yang, F Wang, CF Liu - Autophagy: Biology and Diseases: Technology …, 2021 - Springer
Autophagy is a catabolic process that removes aggregated proteins and damaged
organelles via lysosomal degradation. Increasing evidence suggests that dysfunction of …
organelles via lysosomal degradation. Increasing evidence suggests that dysfunction of …
Choose delicately and reuse adequately: the newly revealed process of autophagy
S Kobayashi - Biological and Pharmaceutical Bulletin, 2015 - jstage.jst.go.jp
Autophagy is a degradation system for intracellular components. One of the roles of
autophagy is the prompt removal of damaged organelles. Another unique role is to supply …
autophagy is the prompt removal of damaged organelles. Another unique role is to supply …
Targeting autophagy drug discovery: Targets, indications and development trends
M Jiang, W Wu, Z Xiong, X Yu, Z Ye, Z Wu - European Journal of Medicinal …, 2024 - Elsevier
Autophagy plays a vital role in sustaining cellular homeostasis and its alterations have been
implicated in the etiology of many diseases. Drugs development targeting autophagy began …
implicated in the etiology of many diseases. Drugs development targeting autophagy began …
Autophagy modulators from traditional Chinese medicine: Mechanisms and therapeutic potentials for cancer and neurodegenerative diseases
Abstract Ethnopharmacological relevance Traditional Chinese medicine (TCM), an ancient
yet still alive medicinal system widely used in East Asia, has played an essential role in …
yet still alive medicinal system widely used in East Asia, has played an essential role in …
Novel pharmacological modulators of autophagy and therapeutic prospects
P Bischoff, E Josset, FJ Dumont - Expert opinion on therapeutic …, 2012 - Taylor & Francis
Introduction: Autophagy is an intracellular process of self-digestion involving the lysosomal
degradation of cytoplasmic organelles and macromolecules. It occurs at low basal levels to …
degradation of cytoplasmic organelles and macromolecules. It occurs at low basal levels to …
Chemical modulators of autophagy as biological probes and potential therapeutics
A Fleming, T Noda, T Yoshimori… - Nature chemical …, 2011 - nature.com
Autophagy is an evolutionarily conserved mechanism for protein degradation that is critical
for the maintenance of homeostasis in man. Autophagy has unexpected pleiotropic functions …
for the maintenance of homeostasis in man. Autophagy has unexpected pleiotropic functions …
Natural autophagy regulators in cancer therapy: a review
Autophagy is a complicated self-eating response of cells to external or internal stimuli. This
process involves cellular degradation through the lysosomes of dysfunctional or …
process involves cellular degradation through the lysosomes of dysfunctional or …
[HTML][HTML] Targeting selective autophagy and beyond: From underlying mechanisms to potential therapies
W Ma, Y Lu, X Jin, N Lin, L Zhang, Y Song - Journal of Advanced Research, 2024 - Elsevier
Background Autophagy is an evolutionarily conserved turnover process for intracellular
substances in eukaryotes, relying on lysosomal (in animals) or vacuolar (in yeast and plants) …
substances in eukaryotes, relying on lysosomal (in animals) or vacuolar (in yeast and plants) …
[HTML][HTML] Natural autophagy blockers, dauricine (DAC) and daurisoline (DAS), sensitize cancer cells to camptothecin-induced toxicity
Autophagy is a cellular bulk degradation pathway implicated in various diseases. Inhibition
of autophagy has been regarded as a new therapeutic strategy for cancer treatment …
of autophagy has been regarded as a new therapeutic strategy for cancer treatment …
Autophagy modulators from traditional Chinese medicine: mechanisms and therapeutic potentials for cancer and neurodegenerative diseases.
WSF Wang ShengFang, WMY Wu MingYue… - 2016 - cabidigitallibrary.org
Abstract Ethnopharmacological relevance: Traditional Chinese medicine (TCM), an ancient
yet still alive medicinal system widely used in East Asia, has played an essential role in …
yet still alive medicinal system widely used in East Asia, has played an essential role in …