Autophagy as a molecular target for cancer treatment

NM Kocaturk, Y Akkoc, C Kig, O Bayraktar… - European Journal of …, 2019 - Elsevier
Autophagy is an evolutionarily conserved catabolic mechanism, by which eukaryotic cells
recycle or degrades internal constituents through membrane-trafficking pathway. Thus …

Plant natural compounds: targeting pathways of autophagy as anti‐cancer therapeutic agents

X Zhang, LX Chen, L Ouyang, Y Cheng… - Cell proliferation, 2012 - Wiley Online Library
Natural compounds derived from plant sources are well characterized as possessing a wide
variety of remarkable anti‐tumour properties, for example modulating programmed cell …

[引用][C] 靶向细胞自噬关键蛋白小分子抑制剂的发现, 确证和机制研究

万伟 - 2019 - 中国科学院大学(中国科学院上海药物 …

Inhibition of autolysosomes by repurposing drugs as a promising therapeutic strategy for the treatment of cancers

AA Al-Bari - All Life, 2022 - Taylor & Francis
Autophagy process coordinates lysosomal destruction of cytoplasmic materials including
damaged organelles and proteins. The double-membranous 'autophagosome'selectively …

Autophagy and metabolic regulation in cancer and its application in drug discovery

SK Prajapat, G Srivastava, S Asthana - Autophagy and Metabolism, 2022 - Elsevier
Autophagy is a conserved catabolic pathway where cytoplasmic materials are delivered to
the lysosome for their degradation. Under basal conditions, autophagy is constitutively …

The role of cell autophagy in cancer and its application in drug discovery

M Hong, N Wang, Y Feng - Cell Death-Autophagy, Apoptosis and …, 2015 - books.google.com
Autophagy is a vital basic phenomenon that widely exists in eukaryotic cells. As one type of
programmed cell death, autophagy has gained much more attention in the past few years …

Plant natural products as autophagy modulators to improve potential cancer therapy

L Fu, C Liu, J Zhang, H Yu - Studies in Natural Products Chemistry, 2023 - Elsevier
Plant natural products are well-characterized to have pharmacological or biological activities
that can be of therapeutic benefits for cancer therapy, which also provide an important …

Natural products as modulator of autophagy with potential clinical prospects.

WPQ Wang PeiQi, ZLJ Zhu LingJuan, SDJ Sun DeJuan… - 2017 - cabidigitallibrary.org
Natural compounds derived from living organisms are well defined for their remarkable
biological and pharmacological properties likely to be translated into clinical use. Therefore …

[HTML][HTML] Natural compounds targeting the autophagy pathway in the treatment of colorectal cancer

YX Du, AA Mamun, AP Lyu, HJ Zhang - International Journal of Molecular …, 2023 - mdpi.com
Autophagy is a highly conserved intracellular degradation pathway by which misfolded
proteins or damaged organelles are delivered in a double-membrane vacuolar vesicle and …

The prospects of therapeutic potential and drug development targeting autophagy in cancer

J Bao, B Liu, C Wu - Autophagy: Biology and Diseases: Clinical Science, 2020 - Springer
Autophagy is a self-protection mechanism of cells. Cells can degrade damaged organelles
and macromolecules in this way to guarantee the growth and development of cells. In recent …