Obesity is an ongoing global health concern and has only recently been recognized as a
chronic disease of energy homeostasis and fuel partitioning. Obesity afflicts 17% of US …

The precipitous growth of pediatric obesity worldwide is having deleterious effects. A change
in the landscape of daily activities, mainly nutrition and physical activity, has the strongest …

The numbers, from pharmacy plans Medco Health Solutions, Express Scripts and the
marketing data collection company Verispan, indicate that hundreds of thousands of …

This work was supported by the Intramural Research Programs of NICHD (ZIAHD00641 to
JAY). JAY is a commissioned officer in the US Public Health Service. The opinions and …

Childhood and adult obesity have increased rapidly over the past 30 years. In 2009, 31.4%
of the boys and 28.2% of the girls in England were either overweight or obese. 1 While adult …

In the mid-1980s, Louis J. Aronne, MD, strolled into a lab at Rockefeller University in New
York where a colleague was breeding mice." I will never forget what he showed me," said …

to address cause, and, when the cause is the many changes in how we live, a
pharmaceutical response is meager at best. We need to modify those lifestyle patterns …

Over the past few decades, pediatric obesity has become a national epidemic. Up to one
third of American children and adolescents currently meet criteria as overweight or obese …

Overweight is present if body weight adjusted for height exceeds a specified cut-off; obesity
implies an excessive fraction of total body weight comprised of fat mass. In clinical practice …