Exploring the benefits of cellular models to uncover bioactive polyphenols for neurodegeneration

R Rosado-Ramos, J Godinho-Pereira… - Current …, 2018 - ingentaconnect.com
Our society is currently experiencing increased lifespan; one of the top causes for the high
incidence of neurodegenerative disorders. The lack of effective treatments delaying or …

Natural polyphenols against neurodegenerative disorders: potentials and pitfalls

A Ebrahimi, H Schluesener - Ageing research reviews, 2012 - Elsevier
Within the last years, a rapidly growing number of polyphenolic compounds with
neuroprotective effects have been described. Many efforts have been made to explore the …

[HTML][HTML] Polyphenols as potential enhancers of stem cell therapy against neurodegeneration

D Rodríguez-Vera, A Abad-García… - Neural Regeneration …, 2022 - journals.lww.com
The potential of polyphenols for treating chronic-degenerative diseases (particularly
neurodegenerative diseases) is attractive. However, the selection of the best polyphenol for …

Natural phenolic compounds with neuroprotective effects

M Tavan, P Hanachi, M de la Luz Cádiz-Gurrea… - Neurochemical …, 2024 - Springer
Neurodegenerative disorders are characterized by mitochondrial dysfunction and
subsequently oxidative stress, inflammation, and apoptosis that contribute to neuronal …

Exploring promising minor natural phenolic compounds in neuroprotection‐related preclinical models

CF Moreira Vasconcelos… - Basic & Clinical …, 2024 - Wiley Online Library
Neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease, are
characterised by the progressive loss of specific neuronal cell populations due to …

Polyphenols beyond barriers: a glimpse into the brain

I Figueira, R Menezes, D Macedo… - Current …, 2017 - ingentaconnect.com
Background: Ageing can be simply defined as the process of becoming older, which is
genetically determined but also environmentally modulated. With the continuous increase of …

[HTML][HTML] Polyphenols: Natural food grade biomolecules for treating neurodegenerative diseases from a multi-target perspective

Z Li, T Zhao, M Shi, Y Wei, X Huang, J Shen… - Frontiers in …, 2023 - frontiersin.org
As natural functional bioactive ingredients found in foods and plants, polyphenols play
various antioxidant and anti-inflammatory roles to prevent the development of disease and …

Polyphenols: multipotent therapeutic agents in neurodegenerative diseases

KS Bhullar, HPV Rupasinghe - Oxidative medicine and cellular …, 2013 - Wiley Online Library
Aging leads to numerous transitions in brain physiology including synaptic dysfunction and
disturbances in cognition and memory. With a few clinically relevant drugs, a substantial …

[HTML][HTML] Novel perspectives for neurodegeneration prevention: effects of bioactive polyphenols

S Crispi, S Filosa - Neural Regeneration Research, 2021 - journals.lww.com
Neurodegenerative diseases are becoming a big challenge for modern society.
Neurodegenerative disorders strongly impact on patient and their caregivers. Moreover …

[HTML][HTML] Bioactive polyphenols and neuromodulation: molecular mechanisms in neurodegeneration

F Di Meo, A Valentino, O Petillo, G Peluso… - International journal of …, 2020 - mdpi.com
The interest in dietary polyphenols in recent years has greatly increased due to their
antioxidant bioactivity with preventive properties against chronic diseases. Polyphenols, by …