雌激素快速作用: 大脑衰老的机会之窗?

I Marchant, J Stojanova, L Acevedo… - 中国神经再生研究(英文 …, 2022 - sjzsyj.com.cn
Estrogen produces several beneficial effects in healthy neurological tissues and exhibits
cardioprotective effects. Hormone therapy has been widely used to treat menopausal …

[HTML][HTML] Estrogen rapid effects: a window of opportunity for the aging brain?

I Marchant, J Stojanova, L Acevedo… - Neural Regeneration …, 2022 - journals.lww.com
Estrogen produces several beneficial effects in healthy neurological tissues and exhibits
cardioprotective effects. Hormone therapy has been widely used to treat menopausal …

[HTML][HTML] The role of estrogen in brain and cognitive aging

JK Russell, CK Jones, PA Newhouse - Neurotherapeutics, 2019 - Elsevier
There are 3 common physiological estrogens, of which estradiol (E2) is seen to decline
rapidly over the menopausal transition. This decline in E2 has been associated with a …

Brain aging modulates the neuroprotective effects of estrogen on selective aspects of cognition in women: a critical review

BB Sherwin, JF Henry - Frontiers in neuroendocrinology, 2008 - Elsevier
Although there is now a substantial literature on the putative neuroprotective effects of
estrogen on cognitive functioning in postmenopausal women, it is replete with …

Estrogen therapy: is time of initiation critical for neuroprotection?

BB Sherwin - Nature Reviews Endocrinology, 2009 - nature.com
According to the'critical period'hypothesis, which attempts to explain the observed
discrepancies in the studies on estrogen and cognition, estrogen therapy effectively …

Estrogen therapy after menopause: role in normal cognition and Alzheimer's disease

J Dumas, C Edgren, P Newhouse - Aging Health, 2006 - Taylor & Francis
Preclinical biological studies in vitro and in vivo as well as epidemiological surveys in
humans strongly support the importance of adequate estrogen support for cognitive function …

Estrogen, cognition and female ageing

AR Genazzani, N Pluchino, S Luisi… - Human reproduction …, 2007 - academic.oup.com
Starting from fetal life, estrogens are crucial in determining central gender dimorphism, and
an estrogen-induced synaptic plasticity is well evident during puberty and seasonal changes …

A mechanism emerges for the critical period hypothesis for estrogen treatment

JH Morrison - Proceedings of the National Academy of …, 2011 - National Acad Sciences
During the past few decades, a significant body of literature has emerged from the basic
science community demonstrating neuroprotective effects and synaptic enhancements …

[PDF][PDF] Estrogens and brain function

A Markou, T Duka, GM Prelevic - Hormones, 2005 - hormones.gr
Cognitive decline is well recognized during ageing but is often accelerated in women after
menopause. Studies have shown that there are significant gender differences in brain …

Teasing out effects of estrogen on the brain

MJ Friedrich - Jama, 2002 - jamanetwork.com
SAN DIEGO—Estrogen is a hormone adept at multitasking. Not only does this ubiquitous
molecule influence reproduction, it plays a role in bone and mineral metabolism, cardiac …