合成生物学助力细菌疫苗研发
章金勇， 顾江， 关山， 李海波， 曾浩， 邹全明 - 合成生物学, 2024 - synbioj.cip.com.cn
细菌感染已成为全球第二大死亡因素, 给人类健康与公共安全造成了巨大威胁.
抗生素一直是治疗细菌感染最为主要的手段, 但越来越严重的耐药问题给传统的抗生素疗法带来 …
抗生素一直是治疗细菌感染最为主要的手段, 但越来越严重的耐药问题给传统的抗生素疗法带来 …
An overview on inactivated and live‐attenuated SARS‐CoV‐2 vaccines
S Khoshnood, M Arshadi, S Akrami… - Journal of Clinical …, 2022 - Wiley Online Library
After about 2 years since severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2),
first infections were detected in Wuhan city of China in December 2019, which was followed …
first infections were detected in Wuhan city of China in December 2019, which was followed …
[PDF][PDF] Synthetic vaccinology at Novartis
PR Dormitzer - … of Sciences Forum on Synthetic Biology …, 2013 - sites.nationalacademies.org
▪ Enzymatic gene assembly without cloning▪ Enzymatic error correction degrades
mismatched DNA▪ High fidelity allows virus rescue in manufacturing cell line while …
mismatched DNA▪ High fidelity allows virus rescue in manufacturing cell line while …
Toolkit for quickly generating and characterizing molecular probes specific for SARS-CoV-2 nucleocapsid as a primer for future coronavirus pandemic preparedness
LJ Sherwood, A Hayhurst - ACS synthetic biology, 2021 - ACS Publications
Generating and characterizing immunoreagents to enable studies of novel emerging viruses
is an area where ensembles of synthetic genes, recombinant antibody pipelines, and …
is an area where ensembles of synthetic genes, recombinant antibody pipelines, and …
Research development and evaluation of SARS-CoV-2 vaccines.
C Liu, X Yi, T Cui, W Wu, F Yan - 2020 - cabidigitallibrary.org
Vaccination plays a leading role in improving immunity, reducing susceptibility and
controlling the occurrence and prevalence of some infectious diseases. In this epidemic …
controlling the occurrence and prevalence of some infectious diseases. In this epidemic …
COVID-19: top 60 drug treatments in development: the biopharma industry is ramping up the development of dozens of potential drug therapies and clinical testing in …
A Philippidis - Genetic Engineering & Biotechnology News, 2020 - liebertpub.com
Alex Philippidis n March 16 at the Kaiser Permanente Washington Health Research Institute
in Seattle, doctors injected 43-year-old Jennifer Haller with the first experimental vaccine …
in Seattle, doctors injected 43-year-old Jennifer Haller with the first experimental vaccine …
基于MS2 噬菌体病毒样颗粒的RT-PCR 检测新型冠状病毒(SARS-CoV-2) 质控品制备
王国强， 于茵茵， 曾华辉， 王旭东， 吴玉彬， 尚立芝… - 中国生物工程 …, 2020 - cqvip.com
目的: 制备热稳定性好, 耐RNase 攻击及可全程监控操作的核酸检测新型冠状病毒阳性质控品.
方法: 分别扩增MS2 噬菌体外壳蛋白CP (含PAC 位点) 基因以及成熟酶蛋白A …
方法: 分别扩增MS2 噬菌体外壳蛋白CP (含PAC 位点) 基因以及成熟酶蛋白A …
SARS-CoV-2 Leading Vaccine Candidates: Progress and Development
Abstract The coronavirus disease 2019 (COVID-19) outbreak that originated in China in
December 2019, spread globally and was declared a public health emergency of …
December 2019, spread globally and was declared a public health emergency of …
新型冠状病毒抗原快速检测研发现状及展望*
陈晨， 胡劲超， 曹姗姗， 门冬 - 中国生物工程杂志, 2021 - manu60.magtech.com.cn
新型冠状病毒肺炎疫情的全球大流行, 对全球公共健康, 社会和经济运转造成了重大影响.
在药物研发迟滞及疫苗有效性未得到充分验证的情况下, 对人群进行大规模的快速筛查 …
在药物研发迟滞及疫苗有效性未得到充分验证的情况下, 对人群进行大规模的快速筛查 …
Engineered ultra-high affinity synthetic antibodies for SARS-CoV-2 neutralization and detection
T Slezak, AA Kossiakoff - Journal of Molecular Biology, 2021 - Elsevier
The Covid-19 pandemic is a centenarial global catastrophe. Similar events are likely to be
recurring with more frequency in the future. The inability to control the virus' impact is caused …
recurring with more frequency in the future. The inability to control the virus' impact is caused …