佐剂是一种添加到疫苗中, 使疫苗能够非特异性地增强机体对抗原的特异性免疫应答的物质,
是疫苗和免疫治疗的重要组分. 为了解决当前市场上小分子和生物制剂佐剂靶向性差 …

Vaccination is one of the most successful medical interventions for the prevention of disease
in the twentieth century. However, with the development of new and less reactogenic …

Polymers are used in several immunological applications, for example in designing new
generation vaccines, implantation studies, therapeutics and for the development of animal …

Vaccines have helped considerably in eliminating some lifethreatening infectious diseases
in past two hundred years. Recently, human medicine has focused on vaccination against …

Stimuli-responsive polymers are gaining importance in immunology not only as carriers for
delivering antigens to target tissues but also as immunologically inert adjuvants. Delivery of …

Activating innate immunity in a controlled manner is necessary for the development of next-
generation therapeutics. Adjuvants, or molecules that modulate the immune response, are …

近年来, 亚单位疫苗, DNA 重组疫苗, 合成肽疫苗等新型疫苗不断涌现, 这些疫苗纯度高,
特异性强. 但其分子小, 免疫原性较差, 难以诱导机体产生有效的免疫应答, 需添加佐剂来增强其 …

The introduction of a synthetic material into the body always affects different body systems,
including the defense system. Synthetic polymers are usually thymus-independent antigens …

Subunit vaccines using recombinant antigens appear as the privileged vaccination
technology for safety reasons but still require the development of carriers/adjuvants ensuring …

疫苗是人类医学史上最伟大的发明之一, 在传染病防治方面起着重要作用.
疫苗一般由免疫原和佐剂组成, 其中佐剂能够帮助机体对免疫原产生有效, 持久的免疫应答 …