The interleukin-20 cytokine family in liver disease

E Caparrós, R Francés - Frontiers in Immunology, 2018 - frontiersin.org
The three main causes of inflammation and chronic injury in the liver are viral hepatitis,
alcohol consumption, and non-alcoholic steatohepatitis, all of which can lead to liver fibrosis …

Interleukin-6: A promising cytokine to support liver regeneration and adaptive immunity in liver pathologies

S Naseem, T Hussain, S Manzoor - Cytokine & growth factor reviews, 2018 - Elsevier
Liver pathologies (fibrosis, cirrhosis, alcoholic, non-alcoholic diseases and hepatocellular
carcinoma) represent one of the most common causes of death worldwide. A number of …

[HTML][HTML] Interleukin-10 and chronic liver disease

LJ Zhang, XZ Wang - World journal of gastroenterology: WJG, 2006 - ncbi.nlm.nih.gov
Abstract Interleukin (IL)-10 is an important immunoregulatory cytokine produced by many
cell populations. Numerous investigations suggest that IL-10 plays a major role in chronic …

The role of interleukin-20 in liver disease: Functions, mechanisms and clinical applications

K Wang, HQ Zhan, Y Hu, ZY Yuan, JF Yang, DS Yang… - Heliyon, 2024 - cell.com
Liver disease is a severe public health concern worldwide. There is a close relationship
between the liver and cytokines, and liver inflammation from a variety of causes leads to the …

Research advances in the association between interleukin-17 and liver diseases

P Yang, Y Huang, H Liu - Journal of Clinical Hepatology, 2017 - pesquisa.bvsalud.org
ABSTRACT Interleukin-17 (IL-17) is a proinflammatory factor produced by T helper 17 cells
and can induce a variety of chemokines which participate in the body's immunoregulation …

[HTML][HTML] Interleukin 22 in liver injury, inflammation and cancer

Y Wu, J Min, C Ge, J Shu, D Tian, Y Yuan… - International Journal of …, 2020 - ncbi.nlm.nih.gov
Abstract Interleukin 22 (IL-22), a member of the IL-10 cytokine family and is an emerging
CD4+ Th cytokine that plays an important role in anti-microbial defense, homeostasis and …

[HTML][HTML] IL-6 pathway in the liver: from physiopathology to therapy

D Schmidt-Arras, S Rose-John - Journal of hepatology, 2016 - Elsevier
Summary Interleukin 6 (IL-6) is a pleiotropic four-helix-bundle cytokine that exerts multiple
functions in the body. In the liver, IL-6 is an important inducer of the acute phase response …

[HTML][HTML] Interleukin-22 in the pathogenesis and potential treatment of liver diseases

S Yin, D Feng - Liver Research, 2017 - Elsevier
Abstract Interleukin (IL)-22, a member of the IL-10 cytokine family, plays critical roles in
tissue repair and host defense. IL-22 binds to its hetereodimeric receptor (R) composed of IL …

Type 3 cytokines in liver fibrosis and liver cancer

MF Molina, MN Abdelnabi, T Fabre, NH Shoukry - Cytokine, 2019 - Elsevier
The type 3 cytokines IL-17 and IL-22 play a crucial, well synchronized physiological role in
wound healing and repairing tissue damage due to infections or injury at barrier surfaces …

Emerging role of interleukins for the assessment and treatment of liver diseases

AL Ali, NP Nailwal, GM Doshi - Endocrine, Metabolic & Immune …, 2022 - ingentaconnect.com
Background: The most common liver diseases are fibrosis, alcoholic liver disease,
nonalcoholic fatty disease, viral hepatitis, and hepatocellular carcinoma. These liver …