正电子发射计算机断层显像在中枢神经系统药物研发中的应用

李思泽, 黄琪, 武晓捷, 王少楠… - 中国临床药理学与 …, 2024 - manu41.magtech.com.cn
正电子发射型计算机断层显像技术(positron emission tomography, PET)
在中枢神经系统(CNS) 药物研发中发挥重要作用. PET 可以定量研究CNS …

The application of positron emission tomography in the research and development of central nervous system drugs

S LI, Q HUANG, X WU, S WANG… - Chinese Journal of …, 2024 - manu41.magtech.com.cn
Positron emission tomography (PET) now plays an important role in the research and
development (R&D) of central nervous system (CNS) drugs. PET could characterize the …

[PDF][PDF] 正电子发射断层显像及其在医药学研究中的应用

唐刚华 - 2002 - jcpu.cpu.edu.cn
摘要目的: 阐述正电子发射断层(PET) 显像的原理及其在临床诊断, 疗效评价和药物研究等方面
的应用. 方法: 参阅有关文献, 对其进行综合, 分析和归纳. 结果和结论: PET …

Positron emission tomography in CNS drug discovery and drug monitoring

M Piel, I Vernaleken, F Rösch - Journal of medicinal chemistry, 2014 - ACS Publications
Molecular imaging methods such as positron emission tomography (PET) are increasingly
involved in the development of new drugs. Using radioactive tracers as imaging probes, PET …

Positron emission tomography in drug development

F van den Berg, EA Rabiner - Modern CNS Drug Discovery: Reinventing …, 2021 - Springer
Central nervous system (CNS) drug development poses some unique challenges for drug
developers in terms of drug delivery, assessment of target engagement, and observation of …

[PDF][PDF] Positron Emission Tomography Imaging: A Quantitative Biomarker in CNS Drug Development

Y Huang, RE Carson - 2012 - medicine.yale.edu
Drug development is a lengthy and costly endeavor. It is estimated that it costs close to one
billion dollars to advance a single drug from discovery to the clinics [1]. This is a significant …

Imaging Techniques for Central Nervous System (CNS) Drug Discovery

L Zhang, A Villalobos - Blood‐Brain Barrier in Drug Discovery …, 2015 - Wiley Online Library
This chapter provides an overview of different types of noninvasive imaging techniques that
can be integrated into the central nervous system (CNS) drug discovery process. It …

Clinical evaluation of CNS drugs with PET

A Takano - Nihon Shinkei Seishin Yakurigaku Zasshi= Japanese …, 2009 - europepmc.org
The utility and possibility of PET in the drug development of the neuropsychiatry field is
discussed in this review. Positron emission tomography (PET) is a nuclear medicine imaging …

正电子发射断层显像对药物研究及开发的价值

朱朝晖 - 首都医药, 2003 - cqvip.com
随着正电子发射断层显像(PET) 技术的迅速发展, 其对药物研究及开发的价值正越来越受到重视.
PET 可以定量测量药物在活体内的分布及随时间的变化. 既可以用发射正电子的核素直接标记 …

[引用][C] 正电子放射性药物的临床应用与进展

李彪, 朱承谟 - 诊断学理论与实践, 2005 - cqvip.com
正电子发射计算机体层摄影仪(positron emission tomography, PET) 是可反映人体功能,
生化代谢及进行分子影像研究的先进功能分子影像设备, PET/CT 将能精确反映人体解剖结构的 …