Long noncoding RNAs in aging and age-related diseases

S Kour, PC Rath - Ageing research reviews, 2016 - Elsevier
Aging is the universal, intrinsic, genetically-controlled, evolutionarily-conserved and time-
dependent intricate biological process characterised by the cumulative decline in the …

Long noncoding RNAs in diseases of aging

J Kim, KM Kim, JH Noh, JH Yoon… - … et Biophysica Acta (BBA …, 2016 - Elsevier
Aging is a process during which progressive deteriorating of cells, tissues, and organs over
time lead to loss of function, disease, and death. Towards the goal of extending human …

Role of lncRNAs in aging and age‐related diseases

J He, C Tu, Y Liu - Aging Medicine, 2018 - Wiley Online Library
Aging is progressive physiological degeneration and consequently declined function, which
is linked to senescence on both cellular and organ levels. Accumulating studies indicate that …

[HTML][HTML] Roles of long noncoding RNAs in aging and aging complications

L Jin, Q Song, W Zhang, B Geng, J Cai - Biochimica et Biophysica Acta …, 2019 - Elsevier
Aging is a universal and time dependent complex biological process, characterized by a
progressive physiological dysfunction and an increased vulnerability to death. Though the …

[HTML][HTML] Long noncoding RNAs (lncRNAs) and the molecular hallmarks of aging

I Grammatikakis, AC Panda, K Abdelmohsen… - Aging (Albany …, 2014 - ncbi.nlm.nih.gov
During aging, progressive deleterious changes increase the risk of disease and death.
Prominent molecular hallmarks of aging are genomic instability, telomere attrition …

Long non-coding RNA: Functional agent for disease traits

S Jain, N Thakkar, J Chhatai, M Pal Bhadra… - RNA biology, 2017 - Taylor & Francis
In recent years, long non-coding RNAs (lncRNAs) have attracted the attention of researchers
with their involvement in all facets of life. LncRNAs are transcripts of more than 200 …

[HTML][HTML] Roles of long non-coding RNAs in the development of aging-related neurodegenerative diseases

YQ Ni, H Xu, YS Liu - Frontiers in Molecular Neuroscience, 2022 - frontiersin.org
Aging-related neurodegenerative diseases, including Alzheimer's disease (AD), Parkinson's
disease (PD), Huntington's disease (HD), and amyotrophic lateral sclerosis (ALS), are …

Long noncoding RNAs and Alzheimer's disease

Q Luo, Y Chen - Clinical interventions in aging, 2016 - Taylor & Francis
Long noncoding RNAs (lncRNAs) are typically defined as transcripts longer than 200
nucleotides. lncRNAs can regulate gene expression at epigenetic, transcriptional, and …

[HTML][HTML] LncRNAs regulatory networks in cellular senescence

PK Puvvula - International journal of molecular sciences, 2019 - mdpi.com
Long noncoding RNAs (lncRNAs) are a class of transcripts longer than 200 nucleotides with
no open reading frame. They play a key role in the regulation of cellular processes such as …

[HTML][HTML] Molecular hallmarks of long non-coding RNAs in aging and its significant effect on aging-associated diseases

SAM Sherazi, A Abbasi, A Jamil, M Uzair… - Neural Regeneration …, 2023 - journals.lww.com
Aging is linked to the deterioration of many physical and cognitive abilities and is the leading
risk factor for Alzheimer's disease. The growing aging population is a significant healthcare …