[PDF][PDF] Expression of STAT family and its potency to prognosis in uterine corpus endometrial carcinoma

L Li, S Li, H Zhou - 2022 - scholar.archive.org
Purpose Signal Transducer and Activators of Transcription (STAT) family is a full set of
transcription factors, acting a pivotal role in normal physiological and pathological process …

[HTML][HTML] Stat3 activation in human endometrial and cervical cancers

CL Chen, FC Hsieh, JC Lieblein, J Brown… - British journal of …, 2007 - nature.com
The activation of signal transducer and activator of transcription 3 (Stat3) has been
implicated in the oncogenesis of cancer and is regarded as a novel target for cancer …

[HTML][HTML] The multifaced role of STAT3 in cancer and its implication for anticancer therapy

M Tolomeo, A Cascio - International journal of molecular sciences, 2021 - mdpi.com
Signal transducer and activator of transcription (STAT) 3 is one of the most complex
regulators of transcription. Constitutive activation of STAT3 has been reported in many types …

STAT3 transcription factor as target for anti-cancer therapy

AM Mohassab, HA Hassan, D Abdelhamid… - Pharmacological …, 2020 - Springer
STATs constitute a large family of transcription activators and transducers of signals that
have an important role in many cell functions as regulation of proliferation and differentiation …

[HTML][HTML] The dual role of STAT1 in ovarian cancer: insight into molecular mechanisms and application potentials

X Li, F Wang, X Xu, J Zhang, G Xu - Frontiers in Cell and …, 2021 - frontiersin.org
The signal transducer and activator of transcription 1 (STAT1) is a transducer protein and
acts as a transcription factor but its role in ovarian cancer (OC) is not completely understood …

[HTML][HTML] STAT3 signaling in ovarian cancer: a potential therapeutic target

R Liang, X Chen, L Chen, F Wan, K Chen, Y Sun… - Journal of …, 2020 - ncbi.nlm.nih.gov
Accumulating evidence has shown that Signal Transducer and Activator of Transcription 3
(STAT3) is thought to be a promising target for cancer therapy as STAT3 is frequently …

IL-6 promotes endometrial cancer cells invasion and migration through signal transducers and activators of transcription 3 signaling pathway

Q Che, X Xiao, M Liu, Y Lu, X Dong, S Liu - Pathology-Research and …, 2019 - Elsevier
Abstract Interleukin (IL)-6 is the most well-known traditional activator of activating signal
transducers and activators of transcription 3 (Stat3). They have been proved to promote …

Comparison of STAT3 with HIF-1alpha, Ob and ObR expressions in human endometrioid adenocarcinomas

A Wincewicz, M Koda, M Sulkowska, L Kanczuga-Koda… - Tissue and Cell, 2008 - Elsevier
Signal transducer and activator of transcription (STAT3) maintained invasiveness of
endometrial cancer cell line. STAT3 mediated signaling for oncogenic growth stimulated by …

[HTML][HTML] Expression of signal transducer and activator of transcription 3 in breast cancer and its clinical significance

G Wei, Z Mingliang, C Yong… - Journal of Cancer …, 2015 - journals.lww.com
Objective: The aim of this study was to investigate the expression of signal transducer and
activator of transcription 3 (STAT3) in breast cancer tissue and normal breast tissue in breast …

STAT3α is oncogenic for endometrial carcinoma cells and mediates the oncogenic effects of autocrine human growth hormone

JZ Tang, XJ Kong, A Banerjee, N Muniraj… - …, 2010 - academic.oup.com
We herein demonstrate an oncogenic role for signal transducer and activator of transcription
(STAT)-3α (the full length STAT3 isoform), which also mediates autocrine human GH (hGH) …