[HTML][HTML] Recommended mass spectrometry-based strategies to identify ricin-containing samples

SR Kalb, DM Schieltz, F Becher, C Astot… - Toxins, 2015 - mdpi.com
Ricin is a protein toxin produced by the castor bean plant (Ricinus communis) together with
a related protein known as R. communis agglutinin (RCA120). Mass spectrometric (MS) …

Rapid and sensitive identification of ricin in environmental samples based on lactamyl agarose beads using LC‐MS/MS (MRM)

L Feldberg, O Schuster, E Elhanany… - Journal of Mass …, 2020 - Wiley Online Library
Ricin, a plant‐derived toxin extracted from the seeds of Ricinus communis (castor bean
plant), is one of the most toxic proteins known. Ricin's high toxicity, widespread availability …

Analysis of active ricin and castor bean proteins in a ricin preparation, castor bean extract, and surface swabs from a public health investigation

DM Schieltz, SC McGrath, LG McWilliams… - Forensic science …, 2011 - Elsevier
In late February 2008, law enforcement officials in Las Vegas, Nevada, discovered in a hotel
room, a copy of The Anarchist Cookbook, suspected castor beans and a “white powder” …

Forensic identification of neat ricin and of ricin from crude castor bean extracts by mass spectrometry

SÅ Fredriksson, AG Hulst, E Artursson… - Analytical …, 2005 - ACS Publications
The protein toxin ricin, which originates from the seeds of Ricinus communis plants, has
been the subject of increased interest, due to its potential terrorist use. Exceptionally, this …

Ricin-like proteins from the castor plant do not influence liquid chromatography-mass spectrometry detection of ricin in forensically relevant samples

ED Merkley, SC Jenson, JS Arce, AM Melville… - Toxicon, 2017 - Elsevier
The toxic protein ricin (also known as RCA60), found in the seed of the castor plant (Ricinus
communis) is frequently encountered in law enforcement investigations. The ability to detect …

[HTML][HTML] Rapid, sensitive and reliable ricin identification in serum samples using LC–MS/MS

L Feldberg, E Elhanany, O Laskar, O Schuster - Toxins, 2021 - mdpi.com
Ricin, a protein derived from the seeds of the castor bean plant (Ricinus communis), is a
highly lethal toxin that inhibits protein synthesis, resulting in cell death. The widespread …

[HTML][HTML] Recommended immunological assays to screen for ricin-containing samples

S Simon, S Worbs, MA Avondet, DM Tracz, J Dano… - Toxins, 2015 - mdpi.com
Ricin, a toxin from the plant Ricinus communis, is one of the most toxic biological agents
known. Due to its availability, toxicity, ease of production and absence of curative treatments …

[HTML][HTML] An international proficiency test to detect, identify and quantify ricin in complex matrices

S Worbs, M Skiba, J Bender, R Zeleny, H Schimmel… - Toxins, 2015 - mdpi.com
While natural intoxications with seeds of Ricinus communis (R. communis) have long been
known, the toxic protein ricin contained in the seeds is of major concern since it attracts …

[HTML][HTML] Quantification of ricin, RCA and comparison of enzymatic activity in 18 Ricinus communis cultivars by isotope dilution mass spectrometry

DM Schieltz, LG McWilliams, Z Kuklenyik, SM Prezioso… - Toxicon, 2015 - Elsevier
The seeds of the Ricinus communis (Castor bean) plant are the source of the economically
important commodity castor oil. Castor seeds also contain the proteins ricin and R …

Capillary electrophoresis to characterize ricin and its subunits with matrix-assisted laser desorption/ionization time-of-flight mass spectrometry

DH Na, CK Cho, YS Youn, Y Choi, KR Lee, SD Yoo… - Toxicon, 2004 - Elsevier
Capillary electrophoresis (CE) and matrix-assisted laser desorption/ionization time-of-flight
mass spectrometry (MALDI-TOF MS) have been employed as highly efficient methods to …