Neuroinflammation plays a fundamental role on the pathophysiology of acute and chronic
neural disorders. Microglia activation is a major event following central nervous system …

Neuroinflammation plays a fundamental role on the pathophysiology of acute and chronic
neural disorders. Microglia activation is a major event following central nervous system …

Microglia, the resident innate immune cells of the central nervous system (CNS), play
important roles in brain development, maintenance, and disease. As brain sentinels …

When ischemic stroke occurs, oxygen and energy depletion triggers a cascade of events,
including inflammatory responses, glutamate excitotoxicity, oxidative stress, and apoptosis …

Microglia/macrophages are the major immune cells involved in the defence against brain
damage. Their morphology and functional changes are correlated with the release of danger …

Microglia-associated neuroinflammation plays an important role in the pathophysiology of
ischemic stroke. Microglial activation and polarization, and the inflammatory response …

Stroke is the second most common cause of death after cancer worldwide and a major
cause of acquired disability in adults. Overwhelming majority of strokes are caused by …

After an ischemic stroke, neurons in the core are rapidly committed to die, whereas neuron
death in the slowly developing penumbra is more amenable to therapeutic intervention …

The incidence of stroke has fallen dramatically in Western countries in the past three
decades. This resounding success is partially the result of superior control of risk factors …

Microglia play a key role in the immune response and inflammatory reaction that occurs in
response to ischemic stroke. Activated microglia promote neuronal damage or protection in …