本研究旨在探索c-Myb 转录因子在调控细胞早期分化和增殖过程中的DNA 特异性识别机制.
我们以鸡髓系基因mim-1 为研究对象, 研究其潜在双c-Myb 结合位点的结合特异性. mim-1 的c …

This study aims to gain insight into the DNA-specific recognition mechanism of c-Myb
transcription factor during the regulation of cell early differentiation and proliferation …

Transcription factor c-Myb plays important roles in cell survival and differentiation in
immature hematopoietic cells. Here we demonstrate that c-Myb is acetylated at the carboxyl …

Background The transcription factor c-Myb is expressed in hematopoietic progenitor cells
and other rapidly proliferating tissues, regulating genes important for proliferation …

已有研究表明c-myb 基因在白血病等癌症中发挥重要的作用, 但是目前关于c-myb
基因的调控机制尚不清楚. 为了探究c-myb 基因启动子区域表观修饰对该基因表达调控的作用 …

c-Myb, known to play a central role in hematopoiesis, is also an important factor involved in
myogenesis. Here, we found that the c-myb gene is expressed in proliferating C2C12 …

The retroviral oncogene v-myb encodes a transcription factor (v-Myb) which activates the
myelomonocyte-specific mim-1 gene, a natural myb target gene, by cooperating with …

Abstract c-Myb, but not avian myeloblastosis virus (AMV) v-Myb, cooperates with C/EBPβ to
regulate transcription of myeloid-specific genes. To assess the structural basis for that …

The biological effects of the cellular c-Myb and the viral v-Myb proteins are strikingly
different. While c-Myb is indispensable for normal hematopoiesis, v-Myb induces acute …

Three members of the human myb gene family (c-myb, A-myb, and B-myb) encode
transcriptional regulators that can bind to specific DNA sequences. High levels of c-myb …