Estrogen receptor α polymorphisms associated with susceptibility to hepatocellular carcinoma in hepatitis B virus carriers

Y Zhai, G Zhou, G Deng, W Xie, X Dong, X Zhang, L Yu… - Gastroenterology, 2006 - Elsevier
Background & Aims: Overexpression of estrogen receptors (ESRs) is implicated in the
development of hepatocellular carcinoma (HCC) in both animal models and humans. We …

[PDF][PDF] Association of estrogen receptor α polymorphisms with susceptibility to chronic hepatitis B virus infection

G Deng, G Zhou, Y Zhai, S Li, X Li, Y Li, R Zhang… - …, 2004 - Wiley Online Library
Several studies have demonstrated that estrogen receptor α (ESR1) participates in the
pathogenesis of persistent hepatitis B virus (HBV) infection. To examine whether …

[HTML][HTML] Hepatocellular carcinoma and estrogen receptors: Polymorphisms and isoforms relations and implications

VD Baldissera, AF Alves, S Almeida, M Porawski… - Medical hypotheses, 2016 - Elsevier
Hepatocellular carcinoma (HCC) is the most common primary tumor of liver and its
incidence continues to increase worldwide. HCC is a disease with multifactorial causes and …

Lack of association between the functional polymorphisms in the estrogen-metabolizing genes and risk for hepatocellular carcinoma

X Yuan, G Zhou, Y Zhai, W Xie, Y Cui, J Cao… - … Biomarkers & Prevention, 2008 - AACR
Estrogens have been proposed to act as tumor promoters and induce
hepatocarcinogenesis. Recently, we observed a significant association between the risk for …

A cis‐acting regulatory variation of the estrogen receptor α (ESR1) gene is associated with hepatitis B virus‐related liver cirrhosis

Z Yan, W Tan, B Xu, Y Dan, W Zhao, C Deng… - Human …, 2011 - Wiley Online Library
The hepatic fibrogenesis and sexual dimorphism of hepatitis B virus‐related liver cirrhosis
(HBV‐LC) are related to estrogen and its receptors. Abnormal expression of estrogen …

Genetic Variations of Estrogen Receptor (ESR) Associated with Hepatitis C Virus-induced Hepatocellular Carcinoma: Scientific Ramifications

A Elmetwalli, M Amer, A Hassan, MAN Eldin… - International Journal of … - neliti.com
Hepatocellular carcinoma (HCC) is the fifth most common Malignancy worldwide and a
major public health concern in Egypt. HCC is a tough condition to cure, and genetic diversity …

Estrogen receptor gene polymorphisms and HBV-induced liver cirrhosis

JP Xie, XQ Gong, DM Tan, F Liu… - … nan da xue xue bao. Yi …, 2006 - europepmc.org
Methods Xba I and Pvu II polymorphisms of ER gene were analyzed in 98 patients with HBV-
induced cirrhosis, 72 patients with chronic hepatitis B, and 84 healthy controls by …

Polymorphisms of estrogen-metabolizing genes and risk of hepatocellular carcinoma in Taiwan females

PH Yin, HC Lee, GY Chau, TY Liu, HC Liu, WY Lui… - Cancer letters, 2004 - Elsevier
Estrogen has been related to the development of hepatocellular carcinoma (HCC). In this
molecular epidemiological study, we used logistic regression to compare the genotype …

Investigation on association of estrogen receptor a polymorphism with susceptibility to hepatitis B virus infection in Han nationality and Yao minority from Guizhou …

LL Long Li, SKR Shan KeRen, ZY Zhao Yan, LY Li Yi… - 2009 - cabidigitallibrary.org
Objective: To investigate the association of estrogen receptor α (ESR1) polymorphism with
susceptibility to hepatitis B virus (HBV) infection in Han nationality and Yao minority from …

Association of ESR1 gene polymorphisms with the susceptibility to Hepatitis B virus infection and the clinical outcomes

J Xie, Y Ding, X Li, R Pu, W Liu, P Li… - Journal of Medical …, 2023 - Wiley Online Library
Estrogen receptor alpha (ESR1) has been implicated in the pathological process of Hepatitis
B virus (HBV) infection and is probably an important determinant for gender differences. In …