[HTML][HTML] Application and prospects of somatic cell reprogramming technology for spinal cord injury treatment
R Yang, J Pan, Y Wang, P Xia, M Tai… - Frontiers in Cellular …, 2022 - frontiersin.org
Spinal cord injury (SCI) is a serious neurological trauma that is challenging to treat. After
SCI, many neurons in the injured area die due to necrosis or apoptosis, and astrocytes …
SCI, many neurons in the injured area die due to necrosis or apoptosis, and astrocytes …
[HTML][HTML] Improving Efficiency of Direct Pro-Neural Reprogramming: Much-Needed Aid for Neuroregeneration in Spinal Cord Injury
DA Chudakova, EM Samoilova, VP Chekhonin… - Cells, 2023 - mdpi.com
Spinal cord injury (SCI) is a medical condition affecting~ 2.5–4 million people worldwide.
The conventional therapy for SCI fails to restore the lost spinal cord functions; thus, novel …
The conventional therapy for SCI fails to restore the lost spinal cord functions; thus, novel …
Cellular transplantation-based evolving treatment options in spinal cord injury
M Wu, H Yuan, K Li, DL Qiu - Cell biochemistry and biophysics, 2015 - Springer
Spinal cord injury (SCI) often represents a condition of permanent neurologic deficit. It has
been possible to understand and delineate the mechanisms contributing to loss of function …
been possible to understand and delineate the mechanisms contributing to loss of function …
Current status of cell-mediated regenerative therapies for human spinal cord injury
T Zhu, Q Tang, H Gao, Y Shen, L Chen, J Zhu - Neuroscience bulletin, 2014 - Springer
During the past decade, significant advances have been made in refinements for
regenerative therapies following human spinal cord injury (SCI). Positive results have been …
regenerative therapies following human spinal cord injury (SCI). Positive results have been …
[HTML][HTML] Neuronal reprogramming in treating spinal cord injury
X Chen, H Li - Neural regeneration research, 2022 - journals.lww.com
Spinal cord injury represents a devastating central nervous system injury that could impair
the mobility and sensory function of afflicted patients. The hallmarks of spinal cord injury …
the mobility and sensory function of afflicted patients. The hallmarks of spinal cord injury …
Cell-based transplantation strategies to promote plasticity following spinal cord injury
CA Ruff, JT Wilcox, MG Fehlings - Experimental neurology, 2012 - Elsevier
Cell transplantation therapy holds potential for repair and functional plasticity following
spinal cord injury (SCI). Stem and progenitor cells are capable of modifying the lesion …
spinal cord injury (SCI). Stem and progenitor cells are capable of modifying the lesion …
Therapeutical strategies for spinal cord injury and a promising autologous astrocyte-based therapy using efficient reprogramming techniques
H Yang, C Liu, CY Wang, Q Zhang, J An, L Zhang… - Molecular …, 2016 - Springer
Spinal cord injury (SCI) is a traumatic event resulting in disturbances to normal sensory,
motor, or autonomic functions, which ultimately impacts a patient's physical, psychological …
motor, or autonomic functions, which ultimately impacts a patient's physical, psychological …
In vivo cell fate reprogramming for spinal cord repair
Spinal cord injury (SCI) can lead to the loss of motor, sensory, or autonomic function due to
neuronal death. Unfortunately, the adult mammalian spinal cord has limited intrinsic …
neuronal death. Unfortunately, the adult mammalian spinal cord has limited intrinsic …
[HTML][HTML] A cutting-edge strategy for spinal cord injury treatment: resident cellular transdifferentiation
YM Fang, WC Chen, WJ Zheng, YS Yang… - Frontiers in Cellular …, 2023 - frontiersin.org
Spinal cord injury causes varying degrees of motor and sensory function loss. However,
there are no effective treatments for spinal cord repair following an injury. Moreover …
there are no effective treatments for spinal cord repair following an injury. Moreover …
Gene-modified stem cells for spinal cord injury: A promising better alternative therapy
Y Feng, Y Li, PP Shen, B Wang - Stem Cell Reviews and Reports, 2022 - Springer
Stem cell therapy holds great promise for the treatment of spinal cord injury (SCI), which can
reverse neurodegeneration and promote tissue regeneration via its pluripotency and ability …
reverse neurodegeneration and promote tissue regeneration via its pluripotency and ability …