Over the past century, age-related diseases, such as cancer, type-2 diabetes, obesity, and
mental illness, have shown a significant increase, negatively impacting overall quality of life …

Over the past century, age-related diseases, such as cancer, type-2 diabetes, obesity, and
mental illness, have shown a significant increase, negatively impacting overall quality of life …

Circadian rhythms orchestrate biochemical and physiological processes in living organisms
to respond the day/night cycle. In mammals, nearly all cells hold self-sustained circadian …

Ageing leads to a functional deterioration of many brain systems, including the circadian
clock—an internal time-keeping system that generates∼ 24-hour rhythms in physiology and …

The increase of life expectancy and the decline of biological functions with advancing age
are impending obstacles for our society. In general, age-related changes can be separated …

The circadian clock coordinates the internal physiology to increase the homeostatic capacity
thereby providing both a survival advantage to the system and an optimization of energy …

Methods and results: Novel work with biological clock genes that oversee circadian rhythm
may meet this critical need by focusing upon the pathways of the mechanistic target of …

The mammalian circadian system is a hierarchically organized system, which controls a 24-
h periodicity in a wide variety of body and brain functions and physiological processes …

The circadian system is the responsible to organise the internal temporal order in relation to
the environment of every process of the organisms producing the circadian rhythms. These …

Worldwide, individuals are living longer due to medical and scientific advances, increased
availability of medical care and changes in public health policies. Consequently, increasing …