[HTML][HTML] RNA m5C 甲基化修饰及其检测技术在肿瘤中的研究进展

吴念, 代鑫, 龚建平 - Advances in Clinical Medicine, 2022 - hanspub.org
RNA 甲基化修饰作为转录后修饰的重要组成部分, 主要包括N6-甲基腺苷(m6A), 5-
甲基胞嘧啶(m5C), N1-甲基腺苷(m1A) 三种修饰类型. 以RNA 亚硫酸氢盐测序(RNA-BisSeq) …

RNA m5C甲基化修饰在肿瘤中的研究进展

张安琪, 安萌, 姜博, 唐文强, 潘丽, 付波 - 中国肿瘤临床, 2021 - cjco.cn
5-甲基胞嘧啶(5-methylcytosine, m 5 C) 是RNA 中重要的甲基化修饰之一,
也是近年来的研究热点. 随着甲基化测序技术的发展, 在编码RNA 及非编码RNA …

m6A 及m5C 甲基化修饰通过促进细胞增殖与转移影响癌症的发生和发展

邵爽, 郭纪伟, 孟玮 - 国际医药卫生导报, 2024 - imhgn.com
在RNA 中已经发现了170 多种化学修饰, RNA 甲基化修饰是一个重要的转录后修饰过程, N6-
甲基腺苷(m 6 A) 和5-甲基胞嘧啶(m 5 C) 普遍存在于真核生物和原核生物中, 使得RNA …

[HTML][HTML] The emerging significance of RNA 5-methylcytosine modification in human cancers

D Li, J Liu, B Zhu - Oncologie, 2024 - degruyter.com
RNA methylation, the most prevalent type of RNA modification, encompasses more than
60% of all known RNA modifications. With the advancement of methylation sequencing …

RNA methylations in human cancers

X Han, M Wang, YL Zhao, Y Yang, YG Yang - Seminars in cancer biology, 2021 - Elsevier
RNA methylations, as the prevalent post-transcriptional modifications, are critical in
regulating various biological processes, such as RNA transcription, splicing, structure …

[HTML][HTML] Advances in RNA cytosine-5 methylation: detection, regulatory mechanisms, biological functions and links to cancer

C Xue, Y Zhao, L Li - Biomarker Research, 2020 - Springer
As an important posttranscriptional modification of RNA, 5-methylcytosine (m 5 C) has
attracted increasing interest recently, with accumulating evidence suggesting the …

The Critical Role of RNA m6A Methylation in Cancer

Q Lan, PY Liu, J Haase, JL Bell, S Hüttelmaier, T Liu - Cancer research, 2019 - AACR
Since the identification of the first RNA demethylase and the establishment of methylated
RNA immunoprecipitation-sequencing methodology 6 to 7 years ago, RNA methylation has …

[HTML][HTML] Biological roles of RNA m5C modification and its implications in Cancer immunotherapy

H Song, J Zhang, B Liu, J Xu, B Cai, H Yang… - Biomarker …, 2022 - Springer
Epigenetics including DNA and RNA modifications have always been the hotspot field of life
sciences in the post-genome era. Since the first mapping of N6-methyladenosine (m6A) and …

m5C 甲基化修饰及其在肿瘤免疫治疗中的研究进展.

陆云洋, 杜维东, 余东升 - Journal of Prevention & Treatment …, 2024 - search.ebscohost.com
表观遗传修饰在真核细胞生物学过程中有重要的调节作用. 肿瘤免疫疗法是治疗癌症的重要手段
和临床策略. 5⁃ 甲基胞嘧啶(5⁃ methylcytosine, m5C) 是继N6 甲基腺苷(N6⁃ …

RNA m6A methylation in cancer

Z Wang, J Zhou, H Zhang, L Ge, J Li… - Molecular …, 2023 - Wiley Online Library
N 6‐methyladenosine (m6A) is one of the most abundant internal modifications in eukaryotic
messenger RNAs (mRNAs) and non‐coding RNAs (ncRNAs). It is a reversible and dynamic …