The blood-brain barrier is the interface through which the brain interacts with the milieu and
consists mainly of a sophisticated network of brain endothelial cells that forms blood vessels …

The blood-brain barrier is the interface through which the brain interacts with the milieu and
consists mainly of a sophisticated network of brain endothelial cells that forms blood vessels …

Alzheimer's disease (AD) is a neurodegenerative disease representing the most common
type of dementia worldwide. The early diagnosis of AD is very difficult to achieve due to its …

Current theories state that Alzheimer's disease (AD) is a vascular disorder that initiates its
pathology through cerebral microvascular abnormalities. Endothelial dysfunction caused by …

Endothelial cells are the main component of the blood-brain barrier (BBB), a vital structure
for maintaining brain homeostasis that is seriously disrupted in various neurological …

Alzheimer's disease (AD) is a neurode-generative disease with complex pathological mecha-
nism characterized by accumulation of amyloid plaques and neurofibrillary tangles in the …

Worldwide, dementia is one of the most prevalent causes of disability. It is a syndrome that
presents significant deterioration of memory, cognition, and behavior. Dementia is a …

The blood vessels of the brain are lined with endothelial cells and it has been long known
that these help to regulate blood flow to the brain. However, there is increasing evidence …

Alzheimer's disease (AD) involves multiple etiologic factors and a complex pathogenesis.
Vascular factors are increasingly implicated in the pathogenesis of AD. In this paper we …

Background The brain is protected by the blood-brain barrier (BBB), constituted by
endothelial cells supported by pericytes and astrocytes. In Alzheimer's disease a …