Fragile X syndrome (FXS) is one of the most prevalent mental retardations. It is mainly
caused by the loss of fragile X mental retardation protein (FMRP). FMRP is an RNA binding …

Epilepsy is reported to occur in 10 to 20% of individuals with fragile X syndrome (FXS). A
frequent seizure/EEG pattern in FXS appears to resemble that of benign focal epilepsy of …

The fragile X mental retardation syndrome is due to the transcriptional silence of the fragile X
gene, FMR1, and to the resulting loss of the FMR1 product, FMRP. The pathogenesis of the …

Simple Summary Fragile X syndrome (FXS) is a neurodevelopmental disorder and remains
the most frequent inherited cause of intellectual disability. Fragile X patients are at great risk …

Epilepsy is detected in about 23% of patients with fragile X syndrome (FXS). Absence or
reduced levels of the fragile X mental retardation protein (FMRP), a global regulator of …

Fragile X syndrome (FXS) is the most common single gene cause of autism and intellectual
disabilities. Humans with FXS exhibit increased anxiety, sensory hypersensitivity, seizures …

Fragile X mental retardation protein (FMRP) is the product of the fragile X mental retardation
1 gene (FMR1), a gene that—when epigenetically inactivated by a triplet nucleotide repeat …

Fragile X syndrome (FXS), resulting solely from the loss of function of the human fragile X
mental retardation 1 (hFMR1) gene, is the most common heritable cause of mental …

Fragile X syndrome is a common inherited form of mental retardation and originates from the
absence of expression of the FMR1 gene. This gene and its two homologues, FXR1 and …

Fragile X syndrome (FXS) is the most common inherited form of human mental retardation,
with an estimated prevalence of one in 4000 boys and one in 8000 girls (Warren & Sherman …