哺乳动物大脑新皮质负责感觉信息整合, 运动协调和高级认知等重要功能.
新皮质主要包含两大类神经元: 谷氨酸能兴奋性投射神经元和γ-氨基丁酸能抑制性中间神经元; …

Neural stem cells are multipotent stem cells that generate functional newborn neurons
through a process called neurogenesis. Neurogenesis in the adult brain is tightly regulated …

Even in the adult brain, neural stem cells in the dentate gyrus and subventricular zone
continue to produce neuronal precursors, which migrate and differentiate into functional …

New neurons are generated throughout life. This discovery has challenged firmly held
concepts about the structural plasticity and regenerative capacity of the mammalian brain. In …

Contrary to the long-held dogma, neurogenesis occurs throughout adulthood, and neural
stem cells reside in the adult central nervous system (CNS) in mammals. The developmental …

神经干细胞是一类具有自我更新能力和多向分化潜能的干细胞. 在特定条件下,
神经干细胞可分化为神经元, 少突胶质细胞和星形胶质细胞从而参与神经功能的修复过程 …

In contrast to mammals, the adult zebrafish brain shows neurogenic activity in a multitude of
niches present in almost all brain subdivisions. Irrespectively, constitutive neurogenesis in …

Neurogenesis is a tightly regulated process in time and space both in the developing
embryo and in adult neurogenic niches. A drastic change in the transcriptome and proteome …

神经干细胞增殖, 存活和分化的过程称为神经发生(neurogenesis). 近20 年的大量实验研究证实
多种动物(包括哺乳动物) 成体脑组织中存在着进行性的神经发生, 可产生新的神经元和神经胶质 …

Generation of new neurons persists in the two restricted regions of adult brain, the dentate
gyrus (DG) of the hippocampus and the subventricular zone (SVZ). Newly generated …