Blood-brain barrier disruption occurs in the early stages of Alzheimer's disease. Recent
studies indicate a link between blood-brain barrier dysfunction and cognitive decline and …

Blood-brain barrier disruption occurs in the early stages of Alzheimer's disease. Recent
studies indicate a link between blood-brain barrier dysfunction and cognitive decline and …

Astrocytes play multifaceted and vital roles in maintaining neurophysiological function of the
central nervous system by regulating homeostasis, increasing synaptic plasticity, and …

Background: In Alzheimer's disease (AD) neuronal degeneration is associated with gliosis
and infiltration of peripheral blood mononuclear cells (PBMCs), which participate in …

Astrocytes were historically classified as supporting cells; however, it is becoming
increasingly clear that they actively contribute to neuronal functioning under normal and …

Astrocytes, which are five-fold more numerous than neurons in the central nervous system
(CNS), are traditionally viewed to provide simple structural and nutritional supports for …

Astrocyte reactivity and neuroinflammation are hallmarks of CNS pathological conditions
such as Alzheimer's disease. However, the specific role of reactive astrocytes is still …

Reactive astrogliosis, a complex process characterized by cell hypertrophy and upregulation
of components of intermediate filaments, is a common feature in brains of Alzheimer's …

Alzheimer's disease (AD) is a neurodegenerative disorder that usually develops slowly and
progressively worsens over time. Although there has been increasing research interest in …

Astrocytes are involved in various processes in the central nervous system (CNS). As the
most abundant cell type in the CNS, astrocytes play an essential role in neuronal …