Objective: This study was designed to determine whether an anti-EGFR/gelonin
immunotoxin (E/rG) in combination with Taxol was against EGFR-expressing tumor …

Background: Tumor growth and progression depend largely on the activity of cell membrane
receptors like epidermal growth factor receptor (EGFR). This receptor plays a significant role …

Objective To evaluate the anti-tumor effect of recombinant toxin EGF-TCS against
transplanted human hepatocellular carcinoma in nude mice. Methods Human hepatocellular …

Pancreatic carcinoma is the fifth leading cause of cancer-related deaths in North America
and Europe. Major reasons for the high mortality rate include the inability to detect …

Purpose Rhabdomyosarcoma (RMS) is a rare and aggressive soft tissue sarcoma with
limited treatment options and a high failure rate during standard therapy. New therapeutic …

Objectives Epithelial growth factor receptor (EGFR), as a malignancy marker, is overly
expressed in multiple solid tumors including colorectal neoplasms, one of the most prevalent …

Purpose Epidermal growth factor receptor (EGFR) plays an important role in the growth and
metastasis of many solid tumors. Strategies that target EGFR hold promising therapeutic …

Purpose Preclinical in vivo analyses of treatment responses are an important prerequisite to
evaluate new therapeutics. Molecular in vivo imaging in the far red (FR)/near infra red (NIR) …

Overexpression of epidermal growth factor receptor (EGFR) plays a significant role in the
development and metastasis of many solid tumors. Strategies based on anti-EGFR …

Background Epidermal growth factor receptor (EGFR) plays an important role in the
progression and tumorigenesis of the various cancers. In this regards, anti-EGFR antibodies …