Peripheral nerve injuries caused by accidents may lead to paralysis, sensory disturbances,
anaesthesia, and lack of autonomic functions. Functional recovery after disconnection of the …

Peripheral nerve injuries caused by accidents may lead to paralysis, sensory disturbances,
anaesthesia, and lack of autonomic functions. Functional recovery after disconnection of the …

Background: Injured peripheral nerves regenerate their lost axons but functional recovery in
humans is frequently disappointing. This is particularly important when injuries require …

Here we used a systems biology approach and artificial intelligence to identify a
neuroprotective agent for the treatment of peripheral nerve root avulsion. Based on …

After nerve injury, both neurons and Schwann cells undergo radical change as they adopt
phenotypes dedicated to support repair (Figure 1). The neurons reprogramme to cell …

The “gold standard” treatment of patients with spinal root injuries consists of delayed
surgical reconnection of nerves. The sooner, the better, but problems such as injury-induced …

CNS neurons do not regenerate after injury, leading to permanent functional deficits.
Although sensory and motor neuron axons do regrow after peripheral nerve injury …

Peripheral nerve injury (PNI) leads to the loss of motor, sensory, and autonomic functions,
and often triggers neuropathic pain. During the last years, many efforts have focused on …

Neurodegenerative processes are preceded by neuronal dysfunction and synaptic
disconnection. Disconnection between spinal motoneuron (MN) soma and synaptic target …

Regeneration of long axons after the spinal cord injury (SCI) will benefit patients with
extensive traumatic damage to the white matter pathways who experience intolerable …