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K Akasaka-Manya - mhlw-grants.niph.go.jp
Discussion In previous studies, we described the N-glycan structures of APP695 produced
by Chinese hamster ovary cells (Sato et al. 1999) and the C17. 2 mouse neural stem cell …

Brain-specific expression of N-acetylglucosaminyltransferase IX (GnT-IX) is regulated by epigenetic histone modifications

Y Kizuka, S Kitazume, M Yoshida… - Journal of Biological …, 2011 - ASBMB
It is well known that biosynthesis of glycans takes place in organ-and tissue-specific
manners and glycan expression is controlled by various factors including …

Alteration of Brain Type N-Glycans in Neurological Mutant Mouse Brain

S Nakakita, S Natsuka, J Okamoto… - Journal of …, 2005 - academic.oup.com
We have previously detected two brain-specific and development-dependent N-glycans [H.
Shimizu, K. Ochiai, K. Ikenaka, K. Mikoshiba, and S. Hase (1993) J. Biochem. 114, 334 …

Demonstration of the expression and the enzymatic activity of N-acetylglucosaminyltransferase IX in the mouse brain

K Inamori, S Mita, J Gu, Y Mizuno-Horikawa… - … et Biophysica Acta (BBA …, 2006 - Elsevier
We recently reported on a brain-specific β1, 6-N-acetylglucosaminyltransferase IX (GnT-IX,
also referred to as GnT-VB), a GnT-V homologue, which acts on α-linked mannose of N …

Peptide Sequence Mapping around Bisecting GlcNAc-Bearing N-Glycans in Mouse Brain

Y Ohkawa, Y Kizuka, M Takata, M Nakano, E Ito… - International Journal of …, 2021 - mdpi.com
N-glycosylation is essential for many biological processes in mammals. A variety of N-glycan
structures exist, of which, the formation of bisecting N-acetylglucosamine (GlcNAc) is …

Use of glycan-targeted antibodies/lectins to study the expression/function of glycosyltransferases in the nervous system

Y Kizuka, K Kanekiyo, S Kitazume… - Glycobiology of the …, 2014 - Springer
In the nervous system, various unique glycans not found in other tissues are expressed on
glycoproteins, and their expression/functions have been studied using specific …

O-GlcNAc Glycosylation and Neurological Disorders

T Lefebvre, ML Caillet-Boudin, L Buée… - Glycobiology and …, 2003 - Springer
O-GLcNAc GLYCOSYLATION AND NEUROLOGICAL DISORDERS Page 1 O-GLcNAc
GLYCOSYLATION AND NEUROLOGICAL DISORDERS Tony Lefebvre1, Marie-Laure …

Molecular cloning of brain-specific GD1α synthase (ST6GalNAc V) containing CAG/glutamine repeats

T Okajima, S Fukumoto, H Ito, M Kiso… - Journal of Biological …, 1999 - ASBMB
A novel member of the mouse CMP-NeuAc: β-N-acetylgalactosaminide α2, 6-
sialyltransferase (ST6GalNAc) subfamily, designated ST6GalNAc V, was identified by …

Truncated, InactiveN-Acetylglucosaminyltransferase III (GlcNAc-TIII) Induces Neurological and Other Traits Absent in Mice That Lack GlcNAc-TIII

R Bhattacharyya, M Bhaumik, TS Raju… - Journal of Biological …, 2002 - ASBMB
N-Acetylglucosaminyltransferase III (GlcNAc-TIII), the product of the Mgat3 gene, transfers
the bisecting GlcNAc to the core mannose of complexN-glycans. The addition of this residue …

The role of the GlcNAcβ1, 2Manα-moiety in mammalian development. Null mutations of the genes encoding UDP-N-acetylglucosamine: α-3-d-mannoside β-1, 2-N …

H Schachter - Biochimica et Biophysica Acta (BBA)-General Subjects, 2002 - Elsevier
The GlcNAcβ1, 2Manα-moiety can be synthesized by at least two mammalian
glycosyltransferases, UDP-GlcNAc: α-3-d-mannoside β1, 2-N-acetylglucosaminyltransferase …