[HTML][HTML] Transcriptional activation by the myb proteins requires a specific local promoter structure
B Ganter, ST Chao, JS Lipsick - FEBS letters, 1999 - Elsevier
The biological effects of the cellular c-Myb and the viral v-Myb proteins are strikingly
different. While c-Myb is indispensable for normal hematopoiesis, v-Myb induces acute …
different. While c-Myb is indispensable for normal hematopoiesis, v-Myb induces acute …
[HTML][HTML] Interaction of the Myb protein with specific DNA binding sites.
RG Ramsay, S Ishii, TJ Gonda - Journal of Biological Chemistry, 1992 - Elsevier
c-myb is expressed predominantly in proliferating immature hemopoietic cells and, like v-
myb, functions as a transcriptional activator that displays sequence-specific DNA binding …
myb, functions as a transcriptional activator that displays sequence-specific DNA binding …
Transcriptional regulation by the carboxyl terminus of c-Myb depends upon both the Myb DNA-binding domain and the DNA recognition site
JW Dubendorff, JS Lipsick - Oncogene, 1999 - nature.com
The c-Myb protein binds to DNA, can regulate transcription, and is required for normal
hematopoiesis in vertebrates. Either amino-or carboxy-terminal truncation of this protein is …
hematopoiesis in vertebrates. Either amino-or carboxy-terminal truncation of this protein is …
Myb binding sites mediate negative regulation of c-myb expression in T-cell lines
J Guerra, DA Withers, LM Boxer - 1995 - ashpublications.org
In hematopoietic cell development, the c-myb transcription factor plays an important role. c-
myb mRNA is expressed at high levels in immature proliferating cells and in leukemic cells …
myb mRNA is expressed at high levels in immature proliferating cells and in leukemic cells …
[HTML][HTML] Two regions in c-myb proto-oncogene product negatively regulating its DNA-binding activity
Y Tanaka, T Nomura, S Ishii - FEBS letters, 1997 - Elsevier
The c-myb proto-oncogeneproduct (c-Myb) is a transcriptional regulator that binds to the
specific DNA sequence. Deletion of the negative regulatory domain (NRD) in the carboxyl …
specific DNA sequence. Deletion of the negative regulatory domain (NRD) in the carboxyl …
Increase in specific DNA binding by carboxyl truncation suggests a mechanism for activation of Myb.
RG Ramsay, S Ishii, TJ Gonda - Oncogene, 1991 - europepmc.org
Oncogenic forms of the c-myb protein (Myb) often exhibit amino-terminal and/or carboxyl-
terminal truncations. When the transcriptional activity of these proteins was examined it was …
terminal truncations. When the transcriptional activity of these proteins was examined it was …
Functional antagonism between members of the myb family: B‐myb inhibits v‐myb‐induced gene activation.
G Foos, S Grimm, KH Klempnauer - The EMBO journal, 1992 - embopress.org
The oncogene v‐myb and its cellular progenitor c‐myb encode nuclear, DNA binding
phosphoproteins that control the expression of certain target genes in immature …
phosphoproteins that control the expression of certain target genes in immature …
Positive autoregulation of c-myb expression via Myb binding sites in the 5'flanking region of the human c-myb gene
NC Nicolaides, R Gualdi, C Casadevall… - … and cellular biology, 1991 - Taylor & Francis
The nuclear proto-oncogene c-myb is preferentially expressed in lymphohematopoietic
cells, in which it plays an important role in the processes of differentiation and proliferation …
cells, in which it plays an important role in the processes of differentiation and proliferation …
Functional domains of the human B-myb gene product
H Nakagoshi, Y Takemoto, S Ishii - Journal of Biological Chemistry, 1993 - ASBMB
Three members of the human myb gene family (c-myb, A-myb, and B-myb) encode
transcriptional regulators that can bind to specific DNA sequences. High levels of c-myb …
transcriptional regulators that can bind to specific DNA sequences. High levels of c-myb …
The myb genes.
KM Weston - Seminars in cancer biology, 1990 - europepmc.org
The v-myb oncogene and its cellular progenitor c-myb are both DNA binding proteins
capable of transcriptional activation, and are implicated in the regulation of the switch …
capable of transcriptional activation, and are implicated in the regulation of the switch …