In recent work, we have shown that cell senescence of mouse fibroblasts in vitro associates
with a build-up of cryptic exons in selected mRNAs, whose level is usually controlled by the …

In recent work, we have shown that cell senescence of mouse fibroblasts in vitro associates
with a build-up of cryptic exons in selected mRNAs, whose level is usually controlled by the …

To evaluate senescence mechanisms, including senescence-associated secretory
phenotype (SASP), in the motor neuron disease model hSOD1-G93A, we quantified the …

To evaluate senescence mechanisms, including senescenceassociated secretory
phenotype (SASP), in the motor neuron disease model hSOD1-G93A, we quantified the …

Recent evidence demonstrates a pathological role for senescent cells in Alzheimer's and
Parkinson's diseases. The present study aimed to show senescence mechanisms including …

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterized by
the progressive loss of upper and lower motor neurons. However, recent reports suggest an …

Cellular senescence is permanent cell cycle arrest resulting from persistent DNA damage
signaling caused by excessive cell divisions, oxidative or other DNA-damaging stress …

Neurodegenerative diseases (NDs) are age-related pathologies that are becoming
increasingly prevalent worldwide. Although the underlying cause of these conditions is still …

Aging of the central nervous system (CNS) leads to motoric and cognitive decline and
increases the probability for neurodegenerative disease development. Astrocytes fulfill …

The concept of senescence as a phenomenon limited to proliferating cells has been
challenged by growing evidence of senescence-like features in terminally differentiated …