Krüppel 样因子2 (KLF2), 神经再生的潜在靶点

S Hansda, P Prateeksha, H Das - 中国神经再生研究(英文版), 2024 - sjzsyj.com.cn
Neurological disorders and injuries lead to the impairment or depletion of neurons in terms
of quantity, structure, or function, resulting in the loss of cognitive, emotional, and physical …

Krüppel-like factor 2 (KLF2), a potential target for neuroregeneration

S Hansda, P Prateeksha, H Das - Neural Regeneration Research - journals.lww.com
Neurological disorders and injuries lead to the impairment or depletion of neurons in terms
of quantity, structure, or function, resulting in the loss of cognitive, emotional, and physical …

[HTML][HTML] Deletion of Krüppel-like factor-4 promotes axonal regeneration in mammals

JH Xu, XZ Qin, HN Zhang, YX Ma, SB Qi… - Neural Regeneration …, 2021 - journals.lww.com
Axonal regeneration plays an important role in functional recovery after nervous system
damage. However, after axonal injury in mammals, regeneration is often poor. The deletion …

敲除Krüppel 样因子4 基因可促进哺乳动物轴突再生?

JH Xu, XZ Qin, HN Zhang, YX Ma, SB Qi… - 中国神经再生研究 …, 2021 - sjzsyj.com.cn
轴突再生在神经系统受损后的功能恢复中起着重要的作用, 但是哺乳动物轴突一旦损伤后,
其再生能力通常较差. Krüppel 样因子4 敲除可促进视网膜神经节细胞中轴突的再生 …

[HTML][HTML] Krüppel-like factor 7 attenuates hippocampal neuronal injury after traumatic brain injury

WY Li, XM Fu, ZD Wang, ZG Li, D Ma… - Neural Regeneration …, 2022 - journals.lww.com
Our previous study has shown that the transcription factor Krüppel-like factor 7 (KLF7)
promotes peripheral nerve regeneration and motor function recovery after spinal cord injury …

[HTML][HTML] Genetic deletion of Krüppel-like factor 11 aggravates traumatic brain injury

C Zhou, P Sun, MH Hamblin, KJ Yin - Journal of Neuroinflammation, 2022 - Springer
Background The long-term functional recovery of traumatic brain injury (TBI) is hampered by
pathological events, such as parenchymal neuroinflammation, neuronal death, and white …

Genetic deletion of Krüppel-like factor 11 aggravates ischemic brain injury

X Tang, K Liu, MH Hamblin, Y Xu, KJ Yin - Molecular neurobiology, 2018 - Springer
Krüppel-like factors (KLFs) belong to the zinc finger family of transcription factors, and their
function in the CNS is largely unexplored. KLF11 is a member of the KLF family, and we …

[HTML][HTML] Therapeutic Targeting of Krüppel-Like Factor 4 and Its Pharmacological Potential in Parkinson's Disease: a Comprehensive Review

MY Zamanian, M Golmohammadi, RS Amin… - Molecular …, 2023 - Springer
Krüppel-like factor 4 (KLF4), a zinc finger transcription factor, is found in different human
tissues and shows diverse regulatory activities in a cell-dependent manner. In the brain …

Krüppel 样因子7 促进创伤性颅脑损伤时JAK2/STAT3 信号通路的活化和抑制神经元凋亡

喻静, 王莹, 王晓宇, 吕忠孝, 刘东明… - 中国组织化学与细胞化学 …, 2023 - cqvip.com
目的探讨Krüppel 样因子7 (KLF7) 在创伤性颅脑损伤(TBI) 后海马区细胞凋亡和神经功能障碍的
保护作用及调控机制. 方法应用控制性皮质撞击(CCI) 法建立小鼠TBI 模型, 侧脑室注射KLF7 …

Krüpple-like factors in the central nervous system: novel mediators in Stroke

KJ Yin, M Hamblin, Y Fan, J Zhang, YE Chen - Metabolic brain disease, 2015 - Springer
Transcription factors play an important role in the pathophysiology of many neurological
disorders, including stroke. In the past three decades, an increasing number of transcription …