Long non-coding RNA (lncRNA) is a kind of non-coding RNA (ncRNA), with a length of 200
nt to 100 kb, that lacks a significant open reading frame (ORF) encoding a protein. lncRNAs …

Long non-coding RNAs (lncRNAs) have recently emerged as key players in many
physiologic and pathologic processes. Although many lncRNAs have been identified, few …

Long noncoding RNAs (lncRNAs) have gained extensive attentions in recent years because
of their potential importance in a variety of biological and pathological processes. In this …

Alzheimer's disease (AD) is a neurodegenerative disorder with progressive damage to brain
cells. It is the leading cause of dementia worldwide that is characterized by impairment of …

With the recent advancement in transcriptome-wide profiling approach, numerous non-
coding transcripts previously unknown have been identified. Among the non-coding …

Accumulation of cellular senescence always forebodes the initialization of aging and cancer.
It is an irreversible process that leads to cell cycle arrest while senescent cells still own …

Long noncoding RNAs (lncRNAs) are a class of transcripts longer than 200 nucleotides with
no open reading frame. They play a key role in the regulation of cellular processes such as …

Elucidating the molecular mechanisms of brain aging remains a significant challenge for
biogerontologists. The discovery of gene regulation by microRNAs (miRNAs) has added a …

Aging is the largest risk factor of major human diseases. Long noncoding RNAs (lncRNAs)
as the key regulatory elements have shown a strong impact on multiple biological processes …

Senescent cells accumulate in normal tissues with advancing age and arise by long‐term
culture of primary cells. Senescence develops following exposure to a range of stress …