Senescent cells accumulate in normal tissues with advancing age and arise by long‐term
culture of primary cells. Senescence develops following exposure to a range of stress …

Centenarians are a successful example of aging and extended longevity, exhibiting
advanced regulation of biological mechanisms and homeostasis. Since human longevity is …

Alzheimer's disease (AD), a heterogeneous neurodegenerative disorder, is the most
common cause of dementia accounting for an estimated 60-80% of cases. The …

Dementia is a progressive cognitive impairment that affects the activities of daily living.
Alzheimer's disease (AD) is the most common form of the dementia worldwide accounting …

Neurodegenerative diseases are gradually becoming the main burden of society. The
morbidity and mortality caused by neurodegenerative diseases remain significant health …

Aging is a universal, intrinsic, and time-dependent biological decay that is linked to intricate
cellular processes including cellular senescence, telomere shortening, stem cell exhaustion …

Dementia is the term used to describe a group of cognitive disorders characterized by a
decline in memory, thinking, and reasoning abilities that interfere with daily life activities …

Background Dysregulation of long noncoding RNA (lncRNA) expression is related to aging
and age-associated neurodegenerative diseases, and the lncRNA expression profile in the …

In the past decades, long noncoding RNAs (lncRNAs) have been indicated to play important
roles in almost every biological process. Aging is a gradual and irreversible biological …

Cellular senescence is a complex stress response that leads to an irreversible state of cell
growth arrest. Senescence may be induced by various stimuli such as telomere shortening …