Abstract c-Myb, but not avian myeloblastosis virus (AMV) v-Myb, cooperates with C/EBPβ to
regulate transcription of myeloid-specific genes. To assess the structural basis for that …

The v-Myb oncoprotein encoded by Avian Myeloblastosis Virus is highly oncogenic, induces
leukemias in chickens and mice and transforms immature hematopoietic cells in vitro. The v …

Oncogenic activation of c-Myb in both avian and murine systems often involves N-terminal
truncation. In particular, the first of three DNA-binding repeats in c-Myb has been largely …

C/EBPɛ is essential for granulocytic differentiation. We investigated the role of C/EBPɛ in
the transcriptional activation of various myeloid-specific genes. We found that two C/EBPɛ …

The retroviral oncogene v-myb encodes a transcription factor (v-Myb) which activates the
myelomonocyte-specific mim-1 gene, a natural myb target gene, by cooperating with …

Three members of the human myb gene family (c-myb, A-myb, and B-myb) encode
transcriptional regulators that can bind to specific DNA sequences. High levels of c-myb …

The c-Myb protein plays a key role in normal hematopoiesis, and truncation results in its
activation to a transforming protein. Truncation of the c-Myb carboxyl terminus also greatly …

The c-myb protooncogene encodes a highly conserved 75-89-kDa transcription factor that
contains three functional domains, an amino-terminal DNA binding domain (DBD), a central …

The c-myb protooncogene encodes a highly conserved transcription factor that functions as
both an activator and a repressor of transcription. The v-myb oncogenes of E26 leukemia …

The c-Myb transcription factor regulates the proliferation and differentiation of hematopoietic
cells, and activated alleles of c-myb induce leukemias and lymphomas in animals. Relatively …