[HTML][HTML] Breast cancer animal models and applications

L Zeng, W Li, CS Chen - Zoological research, 2020 - ncbi.nlm.nih.gov
Breast cancer is the most common malignancy in women. Basic and translational breast
cancer research relies heavily on experimental animal models. Ideally, such models for …

[HTML][HTML] Advances in rodent models for breast cancer formation, progression, and therapeutic testing

C Liu, P Wu, A Zhang, X Mao - Frontiers in Oncology, 2021 - frontiersin.org
Breast cancer is a highly complicated disease. Advancement in the treatment and
prevention of breast cancer lies in elucidation of the mechanism of carcinogenesis and …

[HTML][HTML] Naturally-occurring canine mammary tumors as a translational model for human breast cancer

M Gray, J Meehan, C Martínez-Pérez, C Kay… - Frontiers in …, 2020 - frontiersin.org
Despite extensive research over many decades, human breast cancer remains a major
worldwide health concern. Advances in pre-clinical and clinical research has led to …

[HTML][HTML] Large animal models of breast cancer

P Mondal, KL Bailey, SB Cartwright, V Band… - Frontiers in …, 2022 - frontiersin.org
In this mini review the status, advantages, and disadvantages of large animal modeling of
breast cancer (BC) will be discussed. While most older studies of large animal BC models …

[HTML][HTML] Canine as a comparative and translational model for human mammary tumor

JY Kwon, N Moskwa, W Kang, TM Fan… - Journal of Breast …, 2023 - ncbi.nlm.nih.gov
Despite the advances in research and treatment of human breast cancer, its incidence rate
continues to increase by 0.5% per year, and the discovery of novel therapeutic strategies for …

Animal models for studying prevention and treatment of breast cancer

JE Welsh - Animal models for the study of human disease, 2013 - Elsevier
Breast cancer is one of the most frequently diagnosed malignancies, and despite extensive
molecular and cellular research, the mortality rate remains high. Preclinical testing of new …

The relevance of mouse models to understanding the development and progression of human breast cancer

DC Allred, D Medina - Journal of mammary gland biology and neoplasia, 2008 - Springer
Mouse modeling of human breast cancer has developed tremendously over the past ten
years. Human breast cancer is characterized by enormous biological diversity and …

Experimental mammary carcinogenesis-Rat models

A Alvarado, AI Faustino-Rocha, B Colaco, PA Oliveira - Life Sciences, 2017 - Elsevier
Mammary cancer is one of the most common cancers, victimizing more than half a million of
women worldwide every year. Despite all the studies in this field, the current therapeutic …

Genetically engineered rat models for breast cancer

BMG Smits, MS Cotroneo, JD Haag… - Breast …, 2007 - content.iospress.com
Rat mammary cancers generally resemble many features of human breast cancer. With the
recent developments in rat genetic engineering, the rat has become an excellent model …

[HTML][HTML] Recent Advancement in Breast Cancer Research: Insights from Model Organisms—Mouse Models to Zebrafish

SS Singhal, R Garg, A Mohanty, P Garg, SK Ramisetty… - Cancers, 2023 - mdpi.com
Simple Summary The current article provides an overview of the significance of using
various mouse and zebrafish models in cancer research. In addition, this review discusses …