[HTML][HTML] Hesperidin ameliorates bleomycin-induced experimental pulmonary fibrosis via inhibition of TGF-beta1/Smad3/AMPK and IkappaBalpha/NF-kappaB …

Z Zhou, AD Kandhare, AA Kandhare… - EXCLI …, 2019 - ncbi.nlm.nih.gov
Bleomycin (BLM) is a chemotherapeutic agent which is associated with Idiopathic
pulmonary fibrosis (IPF) due to its chronic administration. Hesperidin, a bioflavonoid has …

Hyperoside attenuates bleomycin-induced pulmonary fibrosis development in mice

J Huang, X Tong, L Zhang, Y Zhang, L Wang… - Frontiers in …, 2020 - frontiersin.org
Idiopathic pulmonary fibrosis (IPF) is a progressive, lethal, and chronic lung disease. There
are no effective drug therapies for IPF. Hyperoside, a flavonoid glycoside, has been proven …

Schisandra Inhibit Bleomycin‐Induced Idiopathic Pulmonary Fibrosis in Rats via Suppressing M2 Macrophage Polarization

Z Guo, S Li, N Zhang, Q Kang… - BioMed Research …, 2020 - Wiley Online Library
Idiopathic pulmonary fibrosis (IPF) is defined as a specific form of chronic, progressive
fibrosing interstitial pneumonia of unknown cause and limited to the lungs. Schisandrae …

Yangqing Chenfei formula alleviates silica-induced pulmonary inflammation in rats by inhibiting macrophage M1 polarization

X Tian, Y Wei, R Hou, X Liu, Y Tian, P Zhao, J Li - Chinese Medicine, 2023 - Springer
Abstract Background Yangqing Chenfei formula (YCF) is a traditional Chinese medicine
formula for early-stage silicosis. However, the therapeutic mechanism is unclear. The …

Danshensu alleviates bleomycin-induced pulmonary fibrosis by inhibiting lung fibroblast-to-myofibroblast transition via the MEK/ERK signaling pathway

H Liu, X Zhang, Y Shao, X Lin, F Dong, X Liu - Bioengineered, 2021 - Taylor & Francis
Pulmonary fibrosis (PF) is a chronic pulmonary interstitial disease, and its pathological
process is closely related to fibroblast–myofibroblast differentiation. Danshensu (DSS) has …

Sirt 1 activator attenuates the bleomycin-induced lung fibrosis in mice via inhibiting epithelial-to-mesenchymal transition (EMT).

L Rong, J Wu, W Wang, RP Zhao… - European Review for …, 2016 - search.ebscohost.com
OBJECTIVE: The aim of this study was to investigate the effect of resveratrol on the
idiopathic bleomycin (BLM)-induced pulmonary fibrosis, which is increasingly recognized as …

Fu-Zheng-Tong-Luo formula promotes autophagy and alleviates idiopathic pulmonary fibrosis by controlling the Janus kinase 2/signal transducer and activator of …

X Zhang, J Su, J Lin, L Liu, J Wu, W Yuan… - Journal of …, 2023 - Elsevier
Abstract Ethnopharmacological relevance Fu-Zheng-Tong-Luo (FZTL) formula is a Chinese
herbal prescription which is used to treat idiopathic pulmonary fibrosis (IPF). We previously …

Baicalin alleviates bleomycin-induced early pulmonary fibrosis in mice via the mitoKATP signaling pathway

M Han, S Wang, X Zhou, P Zhang, Z Han, Y Chen… - Toxicology, 2023 - Elsevier
Bleomycin (BLM), a frequently employed chemotherapeutic agent, exhibits restricted clinical
utility owing to its pulmonary toxicity. Meanwhile, baicalin (BA)—an active ingredient …

[HTML][HTML] Effective-compounds of Jinshui Huanxian formula ameliorates fibroblast activation in pulmonary fibrosis by inhibiting the activation of mTOR signaling

J Li, K Li, Y Tian, P Zhao, X Liu, M Li, Y Bai - Phytomedicine, 2023 - Elsevier
Abstract Background Jinshui Huanxian formula (JHF) ameliorates idiopathic pulmonary
fibrosis patients. Active compounds, including icariin, isoliquiritigenin, nobiletin, peimine …

A standardized herbal extract PM014 ameliorates pulmonary fibrosis by suppressing the TGF-β1 pathway

KH Kim, S Lee, H Lee, D Shin, D Min, M Kim, B Ryu… - Scientific reports, 2018 - nature.com
Idiopathic pulmonary fibrosis (IPF) is a devastating and common chronic lung disease
pathologically characterized by loss of epithelial cells and activation of fibroblasts and …