Blood–brain barrier impairment in Alzheimer disease: stability and functional significance

GL Bowman, JA Kaye, M Moore, D Waichunas… - Neurology, 2007 - AAN Enterprises
Objective: To determine the stability and functional significance of blood–brain barrier (BBB)
integrity in patients with mild to moderate Alzheimer disease (AD). Methods: Thirty-six …

The integrity of the blood–brain barrier in Alzheimer's disease

A Algotsson, B Winblad - Acta neurologica scandinavica, 2007 - Wiley Online Library
Objective–To evaluate the integrity of the blood–brain barrier (BBB) in incident Alzheimer's
disease (AD). Materials and methods–The mean age of the 157 patients (45% men) was …

[HTML][HTML] Increased blood-brain barrier permeability is associated with dementia and diabetes but not amyloid pathology or APOE genotype

S Janelidze, J Hertze, K Nägga, K Nilsson… - Neurobiology of …, 2017 - Elsevier
Blood-brain barrier (BBB) dysfunction might be an important component of many
neurodegenerative disorders. In this study, we investigated its role in dementia using large …

Blood–brain barrier breakdown in relationship to Alzheimer and vascular disease

Z Lin, S Sur, P Liu, Y Li, D Jiang, X Hou… - Annals of …, 2021 - Wiley Online Library
Objective Blood–brain barrier (BBB) breakdown has been suggested to be an early
biomarker in human cognitive impairment. However, the relationship between BBB …

Blood-cerebrospinal fluid barrier permeability in Alzheimer's disease

S Chalbot, H Zetterberg, K Blennow… - Journal of …, 2011 - content.iospress.com
The role of blood-cerebrospinal fluid barrier (BCB) dysfunction in Alzheimer's disease (AD)
has been addressed but not yet established. We evaluated the BCB integrity in 179 samples …

CSF/serum albumin ratio in dementias: a cross-sectional study on 1861 patients

T Skillbäck, L Delsing, J Synnergren, N Mattsson… - Neurobiology of …, 2017 - Elsevier
A connection between dementias and blood-brain barrier (BBB) dysfunction has been
suggested, but previous studies have yielded conflicting results. We examined …

A population study on blood-brain barrier function in 85-year-olds: relation to Alzheimer's disease and vascular dementia

I Skoog, A Wallin, P Fredman, C Hesse, O Aevarsson… - Neurology, 1998 - AAN Enterprises
We investigated blood-brain barrier (BBB) function in relation to Alzheimer's disease (AD)
and vascular dementia (VAD) in the very elderly. Sixty-five 85-year-old persons from a …

Dyslipidemia and Blood‐Brain Barrier Integrity in Alzheimer′ s Disease

GL Bowman, JA Kaye, JF Quinn - Current gerontology and …, 2012 - Wiley Online Library
Background. Blood‐brain barrier (BBB) dysfunction may have a significant role in the
pathogenesis of Alzheimer′ s disease (AD). Modifiable factors associated with BBB …

Cerebrospinal fluid/plasma albumin ratio as a biomarker for blood-brain barrier impairment across neurodegenerative dementias

CS Musaeus, HS Gleerup, P Høgh… - Journal of …, 2020 - content.iospress.com
Background: Previous studies have shown an association between disruption of the blood-
brain-barrier (BBB) and dementias of different etiologies. The protein concentration of …

Blood‐brain barrier breakdown, neuroinflammation, and cognitive decline in older adults

GL Bowman, L Dayon, R Kirkland… - Alzheimer's & …, 2018 - Wiley Online Library
Introduction Blood‐brain barrier (BBB) breakdown is observed in older versus younger
adults and in late‐onset Alzheimer's disease versus age‐matched controls, but its causes …