In zebrafish and other vertebrates, primordial germ cells (PGCs) are a population of
embryonic cells that give rise to sperm and eggs in adults. Any type of genetically …

The zebrafish field is ringing in the new year with a publication from Yonghua Sun's
laboratory (Wang et al., 2023) of a cocktail of germline factors that can induce all cells of the …

The combination of genome editing and primordial germ cell (PGC) transplantation has
enormous significance in the study of developmental biology and genetic breeding, despite …

Primordial germ cells (PGCs) are the only cells in developing embryos that can transmit
genetic information to the next generation. PGCs therefore have considerable potential …

Primordial germ cells (PGCs) are the only cells in developing embryos with the potential to
transmit genetic information to the next generation. PGCs therefore have the potential to be …

Primordial germ cell (PGC) specification early in development establishes the germline for
reproduction and reproductive technologies. Germline replacement (GR) is a powerful tool …

Primordial germ cells (PGCs) are the only cells in developing embryos with the potential to
transmit genetic information to the next generation. In our previous study, a single PGC …

To develop cell mediated gene transfer in fish, establishment of a cell line that has an ability
to differentiate into germ cells is needed. Although the several fish ES-like cell lines have …

Primordial germ cells (PGC) are pivotal for gonadal development and reproductive success.
Though artificial induction of sterility by targeting PGC are gaining popularity due to its …