Therapeutical strategies for spinal cord injury and a promising autologous astrocyte-based therapy using efficient reprogramming techniques

H Yang, C Liu, CY Wang, Q Zhang, J An, L Zhang… - Molecular …, 2016 - Springer
Spinal cord injury (SCI) is a traumatic event resulting in disturbances to normal sensory,
motor, or autonomic functions, which ultimately impacts a patient's physical, psychological …

[HTML][HTML] Advances in neural stem cell therapy for spinal cord injury: safety, efficacy, and future perspectives

S Lee, H Nam, KM Joo, SH Lee - Neurospine, 2022 - ncbi.nlm.nih.gov
Spinal cord injury (SCI) is a devastating central nervous system injury that leads to severe
disabilities in motor and sensory functions, causing significant deterioration in patients' …

[HTML][HTML] Recent advances in endogenous neural stem/progenitor cell manipulation for spinal cord injury repair

J Li, W Luo, C Xiao, J Zhao, C Xiang, W Liu, R Gu - Theranostics, 2023 - ncbi.nlm.nih.gov
Traumatic spinal cord injury (SCI) can cause severe neurological impairments. Clinically
available treatments are quite limited, with unsatisfactory remediation effects. Residing …

Neuronal reprogramming in treating spinal cord injury

X Chen, H Li - Neural regeneration research, 2022 - journals.lww.com
Spinal cord injury represents a devastating central nervous system injury that could impair
the mobility and sensory function of afflicted patients. The hallmarks of spinal cord injury …

[HTML][HTML] Astrocyte transplantation for repairing the injured spinal cord

X Zheng, W Wang - Journal of Biomedical Research, 2022 - ncbi.nlm.nih.gov
Spinal cord injury (SCI) leads to permanent deficits in neural function without effective
therapies, which places a substantial burden on families and society. Astrocytes, the major …

Neural stem cell therapies for spinal cord injury repair: an update on recent preclinical and clinical advances

SM Hosseini, B Borys, S Karimi-Abdolrezaee - Brain, 2024 - academic.oup.com
Traumatic spinal cord injury (SCI) is a leading cause of lifelong disabilities. Permanent
sensory, motor and autonomic impairments after SCI are substantially attributed to …

Reprogramming of astrocytes to neuronal-like cells in spinal cord injury: a systematic review

SD Alizadeh, MR Jalalifar, Z Ghodsi, M Sadeghi-Naini… - Spinal Cord, 2024 - nature.com
Abstract Study design A Systematic Review Objectives To determine the therapeutic efficacy
of in vivo reprogramming of astrocytes into neuronal-like cells in animal models of spinal …

Stem Cell Strategies in Promoting Neuronal Regeneration after Spinal Cord Injury: A Systematic Review

L Bonosi, MP Silven, AA Biancardino… - International Journal of …, 2022 - mdpi.com
Spinal cord injury (SCI) is a devastating condition with a significant medical and
socioeconomic impact. To date, no effective treatment is available that can enable neuronal …

Application and prospects of somatic cell reprogramming technology for spinal cord injury treatment

R Yang, J Pan, Y Wang, P Xia, M Tai… - Frontiers in Cellular …, 2022 - frontiersin.org
Spinal cord injury (SCI) is a serious neurological trauma that is challenging to treat. After
SCI, many neurons in the injured area die due to necrosis or apoptosis, and astrocytes …

[PDF][PDF] Stem cell-based therapies to treat spinal cord injury: a review

Z Shi, H Huang, S Feng - J. Neurorestoratology, 2017 - pdfs.semanticscholar.org
Spinal cord injury (SCI) is a devastating condition and major burden on society and
individuals. Currently, neurorestorative strategies, including stem cell therapy products or …