[HTML][HTML] 合成生物传感器在疾病检测领域的应用技术进展: 设计, 分类和展望

陈雪, 吕毅, 吴荣谦 - Chinese Medical Sciences Journal, 2018 - cmsj.cams.cn
摘要合成生物学通过在细胞中整合入功能性的基因网络, 从而赋予细胞新的功能.
合成生物学领域的科学家们通过过表达, 阻断和重排等手段, 重新编辑细胞的天然基因通路 …

Current technologies of synthetic biosensors for disease detection: design, classification and future perspectives

X Chen, Y Lv, R Wu - Chinese Medical Sciences Journal, 2018 - Elsevier
Synthetic biology aims to endow living cells with new functions by incorporating functional
gene networks into them. By overexpressing, blocking and rewiring native gene pathways …

合成生物学在下一代基因诊断技术中的应用进展

吕海龙, 王建, 吕浩, 王金, 徐勇, 顾大勇 - 合成生物学, 2023 - synbioj.cip.com.cn
近年来, 合成生物学技术取得了飞速的发展, 与此同时也极大地推动了基因诊断领域的技术革新
和应用拓展. 准确诊断疾病和监测治疗后反应的检测方法对有效的临床管理至关重要 …

Synthetic biology for next-generation genetic diagnostics

LV Hailong, W Jian, LV Hao, W Jin… - Synthetic Biology …, 2023 - synbioj.cip.com.cn
In recent years, rapid advances have been made for synthetic biology technologies, which
contribute greatly to technological innovations and applications in genetic diagnostics …

[HTML][HTML] Special Issue “Synthetic Biology for Biosensing in Health and Environmental Applications”

B Wang, C Tan - Biosensors, 2023 - mdpi.com
Biosensors are analytical devices that utilize biological sensing elements, such as enzymes,
antibodies, nucleic acids, or cells, to detect a given analyte. In general, biosensors could be …

Recent advances in developing and applying biosensors for synthetic biology

KA Jones, J Zinkus-Boltz, BC Dickinson - Nano Futures, 2019 - iopscience.iop.org
Biosensors are an indispensable component of the synthetic biologist's toolbox. Informed by
biology and customized through rational design and evolutionary methods, these molecular …

Synthetic cell-based biosensors and methods for discovering novel sensing elements

Y Zhan - … Conference on Biological Engineering and Medical …, 2024 - spiedigitallibrary.org
With the advancement of synthetic biology, cells can be modified and engineered through
gene recombination, gene editing and protein engineering. Given that many elements in …

Modularized synthetic biology enabled intelligent biosensors

C Zhang, H Liu, X Li, F Xu, Z Li - Trends in Biotechnology, 2023 - cell.com
Biosensors that sense the concentration of a specified target and produce a specific signal
output have become important technology for biological analysis. Recently, intelligent …

In vivo biosensors: mechanisms, development, and applications

S Shi, EL Ang, H Zhao - Journal of Industrial Microbiology and …, 2018 - academic.oup.com
In vivo biosensors can recognize and respond to specific cellular stimuli. In recent years,
biosensors have been increasingly used in metabolic engineering and synthetic biology …

Development of next-generation diagnostic tools using synthetic biology

EJ Vojvoda, LR Burrington, JP Oza - New Frontiers and Applications of …, 2022 - Elsevier
Synthetic biology is an intersection between engineering and biology in which biological
components are reconfigured for user-defined applications. To meet global health needs …