BACKGROUND: Long-term sustained release naltrexone has been reported in clinical
application near one year that it can improve emotional state and relieve addiction; …

Objective: To investigate the efficacy of naltrexone in preventing relapse of heroin addiction
among Chinese patients after successful detoxif ication. Methods: 302 heroin addicts were …

This double-blind, randomized, placebo-controlled clinical trial evaluated the impact on
withdrawal symptoms of (i) combining naltrexone with a 4-day buprenorphine taper for short …

Rationale Naltrexone is an opioid antagonist that is currently approved as a treatment for
opioid and alcohol dependence. Although it is highly effective in completely antagonizing …

Rationale: Naltrexone, an opioid antagonist, is currently approved as a treatment for heroin
dependence. However, naltrexone is generally not well accepted by patients, and …

Background and aims Recovery from substance use disorders (SUD) has traditionally been
equated with abstinence." Personal recovery" however emphasizes recovery as a unique …

Drug cues play an important role in relapse to drug use. Naltrexone is an opioid antagonist
that is used to prevent relapse in opioid dependence. Central opioidergic pathways may be …

Background Opioid dependency is a chronic relapsing disorder for which different
therapeutically interventions have been developed. Naltrexone is a non-selective opioid …

Objective: Naltrexone is reported to be a reasonably effective treatment for relapse
prevention for patients with opioid dependence. However, there is a lack of data on outcome …

Background: Heightened response to drug-related cues is a hallmark of addiction. Extended-
release naltrexone (XR-NTX) is a US Food and Drug Administration–approved …