继发于新生血管性年龄相关性黄斑变性的视网膜下纤维化: 机制和潜在治疗目标
J Zhang, X Sheng, Q Ding, Y Wang, J Zhao… - 中国神经再生研究(英文 …, 2025 - sjzsyj.com.cn
视网膜下纤维化是新生血管性年龄相关性黄斑变性(nAMD) 的终末期后遗症, 会造成光感受器,
视网膜色素上皮(RPE) 和脉络膜血管的局部破坏, 导致nAMD 患者永久性中心视力丧失 …
视网膜色素上皮(RPE) 和脉络膜血管的局部破坏, 导致nAMD 患者永久性中心视力丧失 …
[HTML][HTML] 不同抗VEGF 治疗方式对nAMD 患者视网膜下纤维化瘢痕及视力预后的影响
赵晓冉， 巩青云， 周育正， 孙奕斌… - Advances in Clinical …, 2024 - hanspub.org
目的: 探讨不同抗血管内皮生长因子(VEGF) 治疗方式对新生血管性年龄相关性黄斑变性(nAMD)
患者视网膜下纤维化瘢痕及视力预后的影响. 方法: 回顾性收集2019 年6 月至2022 年12 …
患者视网膜下纤维化瘢痕及视力预后的影响. 方法: 回顾性收集2019 年6 月至2022 年12 …
Subretinal fibrosis secondary to neovascular age-related macular degeneration: mechanisms and potential therapeutic targets
J Zhang, X Sheng, Q Ding, Y Wang… - Neural Regeneration …, 2025 - journals.lww.com
Subretinal fibrosis is the end-stage sequelae of neovascular age-related macular
degeneration. It causes local damage to photoreceptors, retinal pigment epithelium, and …
degeneration. It causes local damage to photoreceptors, retinal pigment epithelium, and …
The evolution of fibrosis and atrophy and their relationship with visual outcomes in Asian persons with neovascular age-related macular degeneration
Purpose To describe the rate of development and progression of fibrosis and macular
atrophy (MA) and their relationship with 1-year visual outcomes in Asian participants with …
atrophy (MA) and their relationship with 1-year visual outcomes in Asian participants with …
Molecular mechanisms of TGFβ-mediated EMT of retinal pigment epithelium in subretinal fibrosis of age-related macular degeneration
F Higashijima, M Hasegawa, T Yoshimoto… - Frontiers in …, 2023 - frontiersin.org
Age-related macular degeneration (AMD) is one of the leading causes of blindness in the
elderly, affecting the macula of the retina and resulting in vision loss. There are two types of …
elderly, affecting the macula of the retina and resulting in vision loss. There are two types of …
Subretinal fibrosis in neovascular age-related macular degeneration: current concepts, therapeutic avenues, and future perspectives
L Tenbrock, J Wolf, S Boneva, A Schlecht… - Cell and Tissue …, 2022 - Springer
Age-related macular degeneration (AMD) is a progressive, degenerative disease of the
human retina which in its most aggressive form is associated with the formation of macular …
human retina which in its most aggressive form is associated with the formation of macular …
Myofibroblasts in macular fibrosis secondary to neovascular age-related macular degeneration-the potential sources and molecular cues for their recruitment and …
Age-related macular degeneration (AMD) is the leading cause of blindness in the elderly in
developed countries. Neovascular AMD (nAMD) accounts for 90% of AMD-related vision …
developed countries. Neovascular AMD (nAMD) accounts for 90% of AMD-related vision …
Macrophage to myofibroblast transition contributes to subretinal fibrosis secondary to neovascular age-related macular degeneration
Background Macular fibrosis causes irreparable vision loss in neovascular age-related
macular degeneration (nAMD) even with anti-vascular endothelial growth factor (VEGF) …
macular degeneration (nAMD) even with anti-vascular endothelial growth factor (VEGF) …
Molecular mechanisms of subretinal fibrosis in age-related macular degeneration
Subretinal fibrosis is a result of a wound healing response that follows choroidal
neovascularization in neovascular age-related macular degeneration (nAMD). Although anti …
neovascularization in neovascular age-related macular degeneration (nAMD). Although anti …
Increased Subretinal Fibrosis Secondary To Choroidal Neovascularization In Aged Mice Due To High Levels of Circulating Fibrocytes
J Liu, C Luo, X Tang, D Chen… - … Ophthalmology & Visual …, 2020 - iovs.arvojournals.org
Purpose: Old age is the primary risk factor for age-related macular degeneration (AMD).
More than half of neovascular AMD (nAMD) patients develop macular fibrosis even after …
More than half of neovascular AMD (nAMD) patients develop macular fibrosis even after …