Blood-brain barrier permeability correlates with medial temporal lobe atrophy but not with amyloid-β protein transport across the blood-brain barrier in Alzheimer's …

Y Matsumoto, D Yanase… - Dementia and geriatric …, 2007 - karger.com
Abstract Background/Aims: Alterations in the blood-brain barrier (BBB) may play an
important role in the pathogenesis and treatment of Alzheimer's disease (AD). We …

Blood–brain barrier permeability is associated with different neuroinflammatory profiles in Alzheimer's disease

M Bruno, CG Bonomi, F Ricci… - European journal of …, 2024 - Wiley Online Library
Introduction Inflammation is an important player in Alzheimer's disease (AD), whose effects
can be influenced by the blood–brain barrier (BBB). Here, we investigated the relationship …

Blood–brain barrier permeability in Alzheimer's disease: a case–control MRI study

JM Starr, AJ Farrall, P Armitage, B McGurn… - Psychiatry Research …, 2009 - Elsevier
Blood-brain barrier (BBB) dysfunction may contribute to the risk of Alzheimer's disease (AD).
Dynamic contrast-enhanced magnetic resonance imaging (MRI) was performed repeatedly …

[HTML][HTML] Increased blood-brain barrier permeability is associated with dementia and diabetes but not amyloid pathology or APOE genotype

S Janelidze, J Hertze, K Nägga, K Nilsson… - Neurobiology of …, 2017 - Elsevier
Blood-brain barrier (BBB) dysfunction might be an important component of many
neurodegenerative disorders. In this study, we investigated its role in dementia using large …

Cerebrospinal fluid/plasma albumin ratio as a biomarker for blood-brain barrier impairment across neurodegenerative dementias

CS Musaeus, HS Gleerup, P Høgh… - Journal of …, 2020 - content.iospress.com
Background: Previous studies have shown an association between disruption of the blood-
brain-barrier (BBB) and dementias of different etiologies. The protein concentration of …

Blood-cerebrospinal fluid barrier permeability in Alzheimer's disease

S Chalbot, H Zetterberg, K Blennow… - Journal of …, 2011 - content.iospress.com
The role of blood-cerebrospinal fluid barrier (BCB) dysfunction in Alzheimer's disease (AD)
has been addressed but not yet established. We evaluated the BCB integrity in 179 samples …

Blood–brain barrier dysfunction as a cause and consequence of Alzheimer's disease

MA Erickson, WA Banks - Journal of Cerebral Blood Flow & …, 2013 - journals.sagepub.com
The blood–brain barrier (BBB) plays critical roles in the maintenance of central nervous
system (CNS) homeostasis. Dysfunction of the BBB occurs in a number of CNS diseases …

The integrity of the blood–brain barrier in Alzheimer's disease

A Algotsson, B Winblad - Acta neurologica scandinavica, 2007 - Wiley Online Library
Objective–To evaluate the integrity of the blood–brain barrier (BBB) in incident Alzheimer's
disease (AD). Materials and methods–The mean age of the 157 patients (45% men) was …

Alterations in the blood brain barrier in ageing cerebral cortex in relationship to Alzheimer-type pathology: a study in the MRC-CFAS population neuropathology cohort

AP Viggars, SB Wharton, JE Simpson, FE Matthews… - Neuroscience …, 2011 - Elsevier
Impairment of the blood brain barrier (BBB) in human brain ageing and its relationship to
Alzheimer-type pathology remains poorly defined. We have investigated the BBB in …

Blood–brain barrier impairment in Alzheimer disease: stability and functional significance

GL Bowman, JA Kaye, M Moore, D Waichunas… - Neurology, 2007 - AAN Enterprises
Objective: To determine the stability and functional significance of blood–brain barrier (BBB)
integrity in patients with mild to moderate Alzheimer disease (AD). Methods: Thirty-six …