转录因子促进脊髓损伤后神经再生

Z Finkel, L Cai - 中国神经再生研究(英文版), 2022 - sjzsyj.com.cn
Human spinal cord injury (SCI) results in locomotor and sensory disabilities, which severely
affect the quality of life. To restore function after SCI, it is necessary to repair and reconstruct …

[HTML][HTML] Transcription factors promote neural regeneration after spinal cord injury

Z Finkel, L Cai - Neural Regeneration Research, 2022 - journals.lww.com
Human spinal cord injury (SCI) results in locomotor and sensory disabilities, which severely
affect the quality of life. To restore function after SCI, it is necessary to repair and reconstruct …

[HTML][HTML] Activating endogenous neurogenesis for spinal cord injury repair: recent advances and future prospects

H Yu, S Yang, H Li, R Wu, B Lai, Q Zheng - Neurospine, 2023 - ncbi.nlm.nih.gov
After spinal cord injury (SCI), endogenous neural stem cells are activated and migrate to the
injury site where they differentiate into astrocytes, but they rarely differentiate into neurons. It …

[HTML][HTML] Regulating endogenous neural stem cell activation to promote spinal cord injury repair

EAB Gilbert, N Lakshman, KSK Lau, CM Morshead - Cells, 2022 - mdpi.com
Spinal cord injury (SCI) affects millions of individuals worldwide. Currently, there is no cure,
and treatment options to promote neural recovery are limited. An innovative approach to …

[HTML][HTML] Adult neural progenitor cells transplanted into spinal cord injury differentiate into oligodendrocytes, enhance myelination, and contribute to recovery

SR Sankavaram, R Hakim, R Covacu, A Frostell… - Stem Cell Reports, 2019 - cell.com
Long-term survival and integration of neural progenitor cells (NPCs) transplanted following
spinal cord injury (SCI) have been observed. However, questions concerning the …

Restoring neural circuits after spinal cord injury

A Muheremu, J Wu - Frontiers in Molecular Neuroscience, 2024 - frontiersin.org
Although there are reports of restoring neural circuits to treat spinal cord injury, the results
are not ideal. Lots of work needs to be done to find effective pharmaceutical, cellular, and …

[HTML][HTML] Restoration of spinal cord injury: from endogenous repairing process to cellular therapy

Y Wu, Z Tang, J Zhang, Y Wang, S Liu - Frontiers in cellular …, 2022 - frontiersin.org
Spinal cord injury (SCI) disrupts neurological pathways and impacts sensory, motor, and
autonomic nerve function. There is no effective treatment for SCI currently. Numerous …

神经祖细胞移植与康复相结合促进颈脊髓损伤后的恢复

CM Freria, P Lu - 中国神经再生研究(英文版), 2024 - sjzsyj.com.cn
Efforts to promote recovery of function after human spinal cord injury (SCI) will likely require
interventions targeting the corticospinal tract (CST) motor system: the most important …

[HTML][HTML] Spinal cord injury: molecular mechanisms and therapeutic interventions

X Hu, W Xu, Y Ren, Z Wang, X He, R Huang… - Signal transduction and …, 2023 - nature.com
Spinal cord injury (SCI) remains a severe condition with an extremely high disability rate.
The challenges of SCI repair include its complex pathological mechanisms and the …

脊髓损伤后轴突再生的障碍

JM Kwiecien - 中国神经再生研究(英文版), 2022 - sjzsyj.com.cn
Regeneration of long axons after the spinal cord injury (SCI) will benefit patients with
extensive traumatic damage to the white matter pathways who experience intolerable …