[引用][C] Afrezza: Some questions about a new approach to prandial insulin 关于一种新型餐时胰岛素的一些问题

ZT Bloomgarden - Journal of Diabetes, 2014 - Wiley Online Library
On June 27, the US Food and Drug Administration (FDA) announced its approval of Afrezza
(insulin human) Inhalation Powder, a rapid-acting inhaled insulin to improve glycemic …

Commentary: why was inhaled insulin a failure in the market?

J Oleck, S Kassam, JD Goldman - Diabetes Spectrum, 2016 - Am Diabetes Assoc
OLECK ET AL. disease such as asthma or chronic obstructive pulmonary disease.
Hypoglycemia was demonstrated to be the most common side effect, and frequent glucose …

Afrezza inhaled insulin: the fastest-acting FDA-approved insulin on the market has favorable properties

DC Klonoff - Journal of diabetes science and technology, 2014 - journals.sagepub.com
1072 Journal of Diabetes Science and Technology 8 (6) significant. The early onset of action
of Afrezza compared to insulin aspart likely helped control the postprandial rise in glucose …

Recommendations for initiating use of Afrezza inhaled insulin in individuals with type 1 diabetes

J Pettus, T Santos Cavaiola… - Diabetes Technology & …, 2018 - liebertpub.com
Abstract Treatment with Afrezza®(insulin human) inhalation powder in individuals with type
1 diabetes (T1D) reduces HbA1c levels similar to rapid-acting insulin analogs, but with …

A second-generation inhaled insulin for diabetes mellitus

G Ledet, RA Graves, LA Bostanian… - American Journal of …, 2015 - academic.oup.com
Purpose The pharmacologic properties of a recently approved inhaled insulin product, its
unique delivery system, and the results of clinical safety and efficacy trials are reviewed …

Inhaled insulin: dead horse or rising phoenix?

L Heinemann - Journal of Diabetes Science and Technology, 2018 - journals.sagepub.com
240 Journal of Diabetes Science and Technology 12 (2) artificial pancreas (AP) system may
improve postprandial and overall metabolic control. 4 Recent research has shown that …

[HTML][HTML] Afrezza (insulin human) inhalation powder approved for the treatment of patients with type 1 or type 2 diabetes

L Fala - American health & drug benefits, 2015 - ncbi.nlm.nih.gov
Insulin human inhalation powder is delivered via an inhaler that can be used for up to 15
days from the date of first use. In patients with type 1 diabetes, insulin human inhalation …

Inhaled insulin—what went wrong

J Mitri, AG Pittas - Nature Clinical Practice Endocrinology & Metabolism, 2009 - nature.com
FDA approval of inhaled insulin offered the possibility of a new direction in diabetes care.
Nonetheless, within a year of coming to market, the first inhaled insulin product was …

Afrezza: An inhaled approach to insulin delivery

LW Fleming, JW Fleming, CS Davis - Journal of the American …, 2015 - journals.lww.com
Purpose: The purpose of this article is to educate nurse practitioners about Afrezza. Data
sources: A comprehensive literature search was conducted using MEDLINE for clinical trial …

Initiation of prandial insulin therapy with AIR inhaled insulin or insulin lispro in patients with type 2 diabetes: a randomized noninferiority trial

JL Gross, M Nakano, G Colon-Vega… - Diabetes Technology …, 2009 - liebertpub.com
Background: Insulin initiation in patients with type 2 diabetes is often delayed because of
concerns about injections. Our objective was to compare the effects of AIR® inhaled insulin …