Neurocircuit of chronic pain and pain-induced negative emotions and regulatory mechanisms of electroacupuncture 慢性疼痛及其诱发负面情绪的神经环路及电针调节 …

Z ZHANG, W ZHONG, K ZHANG, LI Man - World Journal of Acupuncture …, 2023 - Elsevier
Chronic pain is a common clinical condition that is frequently linked to negative emotions
such as anxiety and depression. Electroacupuncture (EA) has been shown to have …

Electroacupuncture Alleviates Pain‐Related Emotion by Upregulating the Expression of NPS and Its Receptor NPSR in the Anterior Cingulate Cortex and …

Z Xu, JF Fang, X Xiang, HJ Sun… - Evidence‐Based …, 2020 - Wiley Online Library
Objective. Electroacupuncture (EA) is reported effective in alleviating pain‐related emotion;
however, the underlying mechanism of its effects still needs to be elucidated. The NPS …

A neural circuit associated with anxiety‐like behaviors induced by chronic inflammatory pain and the anxiolytic effects of electroacupuncture

Z Wu, Z Shen, Y Xu, S Chen, S Xiao… - CNS Neuroscience …, 2024 - Wiley Online Library
Aims Negative emotions induced by chronic pain are a serious clinical problem.
Electroacupuncture (EA) is a clinically proven safe and effective method to manage pain …

Electroacupuncture ameliorates chronic inflammatory pain-related anxiety by activating PV interneurons in the anterior cingulate cortex

F Shao, J Fang, M Qiu, S Wang, D Xi, X Shao… - Frontiers in …, 2021 - frontiersin.org
Chronic inflammatory pain is a common clinical disease that tends to be associated with
negative emotions such as anxiety and depression. The anterior cingulate cortex (ACC) is …

[HTML][HTML] Electroacupuncture alleviates anxiety-like behavior in pain aversion rats by attenuating the expression of neuropeptide Y in anterior cingulate cortex

F Shao, J Du, S Wang, J Fang, X Shao, X Jin… - Clinical Complementary …, 2022 - Elsevier
Background Pain is considered as a multidimensional conscious experience that includes a
sensory component and a negative affective-motivational component. Electroacupuncture …

Effect of Electroacupuncture on Pain Perception and Pain‐Related Affection: Dissociation or Interaction Based on the Anterior Cingulate Cortex and S1

Y Shi, S Yao, Z Shen, L She, Y Xu, B Liu… - Neural …, 2020 - Wiley Online Library
Electroacupuncture (EA) can effectively modulate pain perception and pain‐related negative
affect; however, we do not know whether the effect of EA on sensation and affect is parallel …

[HTML][HTML] The involvement of descending pain inhibitory system in electroacupuncture-induced analgesia

Q Lv, F Wu, X Gan, X Yang, L Zhou, J Chen… - Frontiers in integrative …, 2019 - frontiersin.org
Chronic pain is a major health problem, which would impair life quality and reduce
productivity. Electroacupuncture (EA), a modality of medicine based on the theories of …

Electroacupuncture suppresses the pain and pain-related anxiety of chronic inflammation in rats by increasing the expression of the NPS/NPSR system in the ACC

J Du, J Fang, Z Xu, X Xiang, S Wang, H Sun, X Shao… - Brain Research, 2020 - Elsevier
Abstract Background The neuropeptide S/Neuropeptide S receptor (NPS/NPSR) system is
involved in the regulation of anxiety in rodents. Chronic inflammation can induce anxiety …

Electroacupuncture alleviates anxiety-like behaviors induced by chronic neuropathic pain via regulating different dopamine receptors of the basolateral amygdala

M Wu, Y Chen, Z Shen, Y Zhu, S Xiao, X Zhu… - Molecular …, 2022 - Springer
Chronic pain, such as neuropathic pain, causes anxiety and other negative emotions, which
aggravates the pain sensation and increases the risk of chronic pain over time. Dopamine …

Electroacupuncture attenuates neuropathic pain and comorbid negative behavior: the involvement of the dopamine system in the amygdala

XH Zhang, CC Feng, LJ Pei, YN Zhang… - Frontiers in …, 2021 - frontiersin.org
Neuropathic pain (NeuP) is an important clinical problem accompanying negative mood
symptoms. Neuroinflammation in the amygdala is critically involved in NeuP, and the …